Factor VIII

Factor VIII (FVIII) is a blood clotting factor. Defects in the protein result in hemophilia A. FVIII is a cofactor for factor IXa. The images at the left and at the right correspond to one representative FVIII, i.e. the crystal structure of human Factor VIII (2r7e).

3D Structures of Factor VIII

Updated on 18-August-2014

2r7e, 3cdz, 3j2q, 4bdv – hFVIII – human
3hnb, 3hny, 3hob – hFVIII light chain C2 domain
1d7p - hFVIII light chain C2 domain (mutant)
1cfg, 1fac - hFVIII light chain C2 domain membrane-binding peptide - NMR
1iqd - hFVIII light chain C2 domain (mutant) + monoclonal Fab
4ki5 - mFVIII light chain C2 domain + monoclonal Fab – mouse
3j2s - hFVIII light chain
4mo3 - FVIII light chain C2 domain – pig

Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Michal Harel