Factor VIII

Factor VIII (FVIII) is a blood clotting factor. Defects in the protein result in hemophilia A. FVIII is a cofactor for factor IXa.

3D Structures of Factor VIII

Updated on 27-August-2014

2r7e, 3cdz, 3j2q, 4bdv – hFVIII – human
3hnb, 3hny, 3hob – hFVIII light chain C2 domain
1d7p - hFVIII light chain C2 domain (mutant)
1cfg, 1fac - hFVIII light chain C2 domain membrane-binding peptide - NMR
1iqd - hFVIII light chain C2 domain (mutant) + monoclonal Fab
4ki5 - mFVIII light chain C2 domain + monoclonal Fab – mouse
3j2s - hFVIII light chain
4mo3 - FVIII light chain C2 domain – pig

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Alexander Berchansky, Michal Harel