2kkr | pdb_00002kkr

Solution structure of SCA7 zinc finger domain from human ataxin-7 protein

spinqualitylabelsall models 2kkr, 20 NMR models Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 2kkr is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: ZN Gene: ATXN7, SCA7 (Homo sapiens) Resources: FirstGlance, OCA, RCSB, PDBsum Disease [ATX7_HUMAN] Spinocerebellar ataxia type 7. The disease is caused by mutations affecting the gene represented in this entry. Function [ATX7_HUMAN] Acts as component of the STAGA transcription coactivator-HAT complex. Mediates the interaction of STAGA complex with the CRX and is involved in CRX-dependent gene activation. Necessary for microtubule cytoskeleton stabilization. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

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