3co8 | pdb_00003co8

Crystal structure of alanine racemase from Oenococcus oeni

spinqualitylabelsall models 3co8, resolution 1.70Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3co8 is a 2 chain structure with sequence from Oenococcus oeni psu-1. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: PLP NonStd Res: MSE Gene: OEOE_0162 (Oenococcus oeni PSU-1) Activity: Alanine racemase, with EC number 5.1.1.1 Resources: FirstGlance, OCA, RCSB, PDBsum, TOPSAN Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. Publication Abstract from PubMed The crystal structure of alanine racemase from Oenococcus oeni has been determined at 1.7 A resolution using the single-wavelength anomalous dispersion (SAD) method and selenium-labelled protein. The protein exists as a symmetric dimer in the crystal, with both protomers contributing to the two active sites. Pyridoxal 5'-phosphate, a cofactor, is bound to each monomer and forms a Schiff base with Lys39. Structural comparison of alanine racemase from O. oeni (Alr) with homologous family members revealed similar domain organization and cofactor binding. Structure of alanine racemase from Oenococcus oeni with bound pyridoxal 5'-phosphate.,Palani K, Burley SK, Swaminathan S Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Jan 1;69(Pt 1):15-9. doi: , 10.1107/S1744309112047276. Epub 2012 Dec 25. PMID:23295479 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See Also Alanine racemase

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