<StructureSection load='1hqg' size='340' side='right' caption='Structure of rat arginase containing Mn+2 (purple) complex with ornithine and urea (PDB code 1hqg).' scene=>
Function
Arginase (Arg) catalyzes the conversion of arginine to ornithine and urea. Arg is the final enzyme in the urea cycle. Arg requires 2 manganese ions for functioning.
Disease
Relevance
Structural highlights
3D structures of arginase
Updated on 17-November-2014
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- Arginase
- Mn containing arginase
- 1rla, 2rla – rArg + Mn – rat
- 3rla, 4rla, 5rla, 1hqx, 1p8m, 1p8n, 1p8o, 1p8p, 1p8q, 1p8r, 1p8s, 1ta1, 1tbh, 1tbj, 1tbl, 3e8q, 3e8z – rArg (mutant) + Mn
- 1wva, 2pha, 2zav – hArg + Mn
- 1wvb – hArg (mutant) + Mn
- Mn containing arginase complexes
- 1d3v, 1hq5 – rArg + Mn + Arg analog
- 1hqf, 1hqh – rArg + Mn + hydroxyl-Arg
- 1hqg – rArg (mutant) + Mn + ornithine + urea
- 1r1o, 1t4p, 1t4r, 1t4t, 1t5f – rArg + Mn + inhibior
- 1t4s – rArg + Mn + valine
- 1t5g – rArg + Mn + Arg
- 1zpe, 1zpg – rArg Mutant) + Mn + alkylamine derivative
- 3e9b – rArg (mutant) + Mn + Br-ethyl cysteine
- 2aeb, 2pll – hArg + Mn + Arg analog
- 2pho – hArg + Mn + thiosemicarbazide
- 3dj8 – hArg + Mn + amino-epoxy octanoic acid
- 3e6k, 3e6v – hArg (mutant) + Mn + Arg analog
- 3f80 – hArg + Mn + nitro-norleucine
- 3kv2, 3lp7 – hArg + Mn + nor-ω-hydroxy-Arg
- 3gmz – hArg + Mn + ornithine
- 3gn0 – hArg + Mn + ornithine derivative
- 3lp4 – hArg + Mn + lysine
- 3mfv, 3mfw – hArg + Mn + histidine derivative
- 3mjl – hArg + Mn + amino-imidazole
- 3sjt, 3skk, 4hww, 4hxq, 4ie1 – hArg + Mn + inhibitor
- 4fci – hArg + Mn + amino-guanidino propionate
- Co containing arginase
- 3th7, 3the – hArg + Co
- 3thh – hArg + Co + Arg analog
- 3thj – hArg + Co + ornithine
- 4fck – hArg + Co + amino-guanidino propionate
- Ni containing arginase
- 4gsm – hArg + Ni
- 4gsv – hArg + Ni + Arg analog
- Zn containing arginase
- 4gsz – hArg + Zn + Arg analog
- Mn and Zn containing arginase
- 4gwc – hArg + Mn + Zn
- 4gwd – hArg + Mn + Zn + Arg analog
References
