Gelsolin

File:3ffn.jpg

Gelsolin (GLS) is a protein regulator of actin assembly and disassembly. The images at the top and at the right correspond to one representative gelsolin structure, i.e. the human gelsolin (3ffn), it has dimeric form. It contains 6 homologous domains S1 to S6.

3D Structures of GLS

Updated on 26-November-2014

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• GLS
  • 3ffn – hGLS – human
    
  • 2fgh – hoGLS+ATP – horse
    
  • 1d0n - hoGLS
    
  • 2x1o, 2x1p, 2x1q – GLS nanobody - Llama
• GLS domains S1-S3
  • 3ffk – hGLS domains S1-S3+actin
    
  • 1rgi - hoGLS domains S1-S3+actin
    
• GLS domains S4-S6
  • 1h1v - hGLS domains S4-S6+actin
    
  • 1nph - GLS domains S4-S6+Ca – mouse
    
• GLS domain S1
  • 2ff3 - hGLS domain S1+N-WASP+actin
    
  • 2ff6 - hGLS domain S1+Ciboulot domain 2+actin
    
  • [1mdu]] - hGLS domain S1+chActin – chicken
    
  • 1d4x - hGLS domain S1+CeActin+Mg-ATP – Caenorhabditis elegans
    
  • 1esv - hGLS domain S1+rActin+latrunculin – rabbit
    
  • 1eqy - hGLS domain S1+rActin
    
  • 1yvn - hGLS domain S1+yActin (mutant) – yeast
    
  • 1yag - hGLS domain S1+yActin
    
  • 1t44 - hGLS domain S1-thymosin β-4 C-terminal fusion+rActin
    
  • 1kcq – hGLS domainS1+Cd
    
  • 1c0f - hGLS domain S1+DdActin+Ca-ATP - Dictyostelium discoideum
    
  • 1c0g, 1dej - hGLS domain S1+DdActin (mutant)
    
  • 3a5l, 3a5m, 3a5n, 3a5o - hGLS domain S1 (mutant)+DdActin (mutant)
    
  • 3ci5, 3cip, 1nlv – DdGLS domain S1+actin
    
  • 1nm1 - DdGLS domain S1+actin+Mg-ATP
    
  • 3cjb - rGLS domain S1+rActin
    
  • 3cjc - rGLS domain S1+rActin+DNAse I
    
  • 1nmd - hGLS domain S1+actin+Ca+ATP
    
• GLS C-terminal
  • 2fh1, 2fh2, 2fh3, 2fh4 – hGLS C-terminal
    
  • 1p8x - hGLS C-terminal+Ca
    
  • 1p8z – hGLS fraction+rActin
    

Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Jaime Prilusky, Michal Harel