4j6g | pdb_00004j6g

CRYSTAL STRUCTURE OF LIGHT AND DcR3 COMPLEX

spinqualitylabelsall models 4j6g, resolution 2.40Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4j6g is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: BMA, CL, MG, NAG, MAN Related: 4en0, 3k51, 3mi8, 3mhd Gene: TNFSF14, HVEML, LIGHT, UNQ391/PRO726 (Homo sapiens), TNFRSF6B, DCR3, TR6, UNQ186/PRO212 (Homo sapiens) Resources: FirstGlance, OCA, RCSB, PDBsum Function [TNF14_HUMAN] Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus. [TNF6B_HUMAN] Decoy receptor that can neutralize the cytotoxic ligands TNFS14/LIGHT, TNFSF15 and TNFSF6/FASL. Protects against apoptosis. See Also Tumor necrosis factor receptor

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