3w0u | pdb_00003w0u

human Glyoxalase I with an N-hydroxypyridone inhibitor

spinqualitylabelsall models 3w0u, resolution 1.70Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3w0u is a 2 chain structure with sequence from Bionectria wenpingii. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: HPW, ZN Related: 3vw9, 3w0t Gene: GLO1 (Bionectria wenpingii) Activity: Lactoylglutathione lyase, with EC number 4.4.1.5 Resources: FirstGlance, OCA, RCSB, PDBsum Function [LGUL_HUMAN] Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. Involved in the regulation of TNF-induced transcriptional activity of NF-kappa-B.

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