4mak | pdb_00004mak

Crystal structure of a putative ssRNA endonuclease Cas2, CRISPR adaptation protein from E.coli

spinqualitylabelsall models 4mak, resolution 1.10Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4mak is a 2 chain structure with sequence from Escherichia coli str. k-12 substr. mg1655. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: PEG Gene: ygbF, cas2, b2754, JW5438 (Escherichia coli str. K-12 substr. MG1655) Resources: FirstGlance, OCA, RCSB, PDBsum Function [CAS2_ECOLI] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity). See Also Endonuclease

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