2uyh | pdb_00002uyh

HHAI DNA METHYLTRANSFERASE S87Q-Q237S MUTANT COMPLEX WITH 13MER GCGC-GMGC OLIGONUCLEOTIDE AND SAH

spinqualitylabelsall models 2uyh, resolution 2.63Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 2uyh is a 3 chain structure with sequence from Haemophilus haemolyticus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: SAH, SO4 NonStd Res: 5CM Related: 10mh, 1fjx, 1hmy, 1m0e, 1mht, 1skm, 1svu, 2c7o, 2c7p, 2c7q, 2c7r, 2hmy, 2uyc, 3mht, 4mht, 5mht, 6mht, 7mht, 8mht, 9mht Activity: DNA (cytosine-5-)-methyltransferase, with EC number 2.1.1.37 Resources: FirstGlance, OCA, RCSB, PDBsum Function [MTH1_HAEPH] This methylase recognizes the double-stranded sequence GCGC, causes specific methylation on C-2 on both strands, and protects the DNA from cleavage by the HhaI endonuclease. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also DNA methyltransferase HhaI DNA methyltransferase

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