Albumin

spinqualitylabelsall models Human serum albumin (PDB code 1bm0) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Albumin (Alb) is water-soluble protein. Serum albumin (SA) is the most abundant blood plasma protein. SA serves as carrier of fatty acids, bilirubin, ions and drugs. For details on human serum albumin see User:Neeharika Pothuri/Human Serum Albumin Molecular Playground/Human Serum Albumin STRUCTURE 1BM0 Albumin (Hebrew). Investigation on the Site-Selective Binding of Bovine Serum Albumin by Erlotinib Hydrochloride The binding mode of erlotinib hydrochloride (ET), a targeted anticancer drug, to bovine serum albumin (BSA) was investigated through 1H NMR, spectroscopic, thermodynamic and molecular modeling methods. Each subdomain is marked with a different colour (red for subdomain IA; orange, IB; cyan, IIA; yellow, IIB; green, IIIA; darkmagenta, IIIB). From these methods, the binding parameters, binding site, binding distance, and conformational changes were obtained. Site marker competitive experiments demonstrated that the binding site was located in the hydrophobic pocket of site I (subdomain IIA). The docking modeling agreed with the results of the fluorescence and displacement experiments.

3D Structures of albumin

Updated on 27-January-2016

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• Human serum albumin
  • 1e78, Molecular Playground/Human Serum Albumin, STRUCTURE 1BM0, Albumin (Hebrew), 3sqj, 4g03, 4g04, 4k2c - hSA – human
• Human serum albumin binary complex
  • 2ydf – hSA + iophenoxic acid
    
  • 2xvq, 2xvu, 2xw0, 2xw1 - hSA + dansyl derivative
    
  • 3lu6, 3ju7, 3lu8, 2bx8, 2bxa, 2bxb, 2bxc, 2bxd, 2bxe, 2bxf, 2bxg, 2bxh, 2bxi, 2bxk, 2bxl, 2bxm, 2bxn,2bxo, 2bxp, 2bxq, 3lu7, 4l8u, 4l9k, 4l9q, 4la0, 4lb2, 4lb9 – hSA + drug
    
  • 4iw1, 4iw2 – hSA + monosaccharide
    
  • 3jqz – hSA + lidocaine
    
  • 3jry - hSA + sulfate
    
  • 4emx – has + Cl
    
  • 1n5u - hSA + heme
    
  • 3a73 - hSA + prostaglandin
    
  • 2vuf, 2vue - hSA + bilirubin derivative
    
  • 1gni, 1gnj, 1e7h, 1e7e, 1e7f, 1e7i, 1bke, 1bj5, 3tdl, 4e99, 4bke - hSA + fatty acid
    
  • 1hk1 - hSA + thiroxine
    
  • 2hk2, 1hk3, 1hk2 - hSA (mutant) + thiroxine
    
  • 1e7a, 1e7b - hSA + general anesthetic
    
  • 1tf0 - hSA + peptostreptococcal albumin-binding protein GA module
    
  • 2esg - hSA + immunoglobulin A1
    
  • 1ysx - hSA + anti-apoptotic ligand – NMR
    
  • 4hgk, 4hgm – hSA + shark antibody
    
• Human serum albumin ternary complex
  • 2xsi, 2xvv, 2xvw – hSA + dansyl derivative + myristic acid
    
  • 3cx9 - hSA + lysophospholipid + myristic acid
    
  • 1e7g - hSA + fatty acid + myristic acid
    
  • 1h9z, 1ha2 - hSA + warfarine + myristic acid
    
  • 1e7c - hSA + general anesthetic + myristic acid
    
  • 1hk4 - hSA + thiroxine + myristic acid
    
  • 1hk5 - hSA (mutant) + thiroxine + myristic acid
    
  • 1o9x - hSA + hemin + myristic acid
    
  • 3uiv - hSA + amantadine + myristic acid
    
  • 3b9l - hSA + AZT + myristic acid
    
  • 2i2z - hSA + aspirin + myristic acid
    
  • 2i30 - hSA + salicylic acid + myristic acid
    
  • 3b9m - hSA + AZT + salicylic acid + myristic acid
    
  • 2vdb - hSA + peptostreptococcal albumin-binding protein GA module + naproxen
    
  • 4k71, 4n0f – hSA + Igg receptpr + β-2-microglobulin
    
  • 4n0u – hSA + Igg receptpr + β-2-microglobulin + Ig γ-1 chain C
    
• Other serum albumins
  • 3v03, 4f5s - bSA – bovine
    
  • 3v08, 4f5t, 4f5u – hoSA – horse
    
  • 3v09, 4f5v – rSA – rabbit
    
  • 4luf – sSA – sheep
    
  • 3vvj – SA – emu
    
  • 4j2v – hoSA + diiodosalicilate
    
  • 4jk4 – bSA + diiodosalicilate
    
  • 4luh – sSA + diiodosalicilate
    
  • 4or0 – bSA + drug
    
  • 4ot2 – hoSA + drug
    
  • 4po0 – rSA + drug
    
• Albumin
  • 1s6d – Alb 8 – sunflower – NMR
    
  • 1wba – Alb 1 – winged bean
    
  • 1p8b – Alb 1 – pea
    
  • 1psy – Alb – castor bean - NMR
    
  • 3lp9 – Alb hemopexin domain – Lathyrus sativus
    
  • 2lvf – Alb – Brazil nut

References

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