Gelsolin

File:3ffn.jpg

Function

Gelsolin (GLS) is a protein regulator of actin assembly and disassembly.

Structural highlights

The image at the top left corresponds to the human gelsolin (3ffn), it has dimeric form. It contains 6 homologous domains S1 to S6.

3D Structures of GLS

Updated on 06-March-2016

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• GLS
  • 3ffn – hGLS – human
    
  • 2fgh – hoGLS+ATP – horse
    
  • 1d0n - hoGLS
    
  • 2x1o, 2x1p, 2x1q – GLS nanobody - Llama
• GLS domains S1-S3
  • 3ffk – hGLS +actin
    
  • 1rgi - hoGLS +actin
    
• GLS domains S4-S6
  • 1h1v - hGLS +actin
    
  • 1nph - mGLS +Ca – mouse
    
• GLS domain S1
  • 2ff3 - hGLS +N-WASP+actin
    
  • 2ff6 - hGLS +Ciboulot domain 2+actin
    
  • [1mdu]] - hGLS +chActin – chicken
    
  • 1d4x - hGLS +CeActin+Mg-ATP – Caenorhabditis elegans
    
  • 1esv - hGLS +rActin+latrunculin – rabbit
    
  • 1eqy - hGLS +rActin
    
  • 1yvn - hGLS +yActin (mutant) – yeast
    
  • 1yag - hGLS +yActin
    
  • 1t44 - hGLS/thymosin β-4 C-terminal fusion+rActin
    
  • 1kcq – hGLS +Cd
    
  • 1c0f, 1mdu, 1nmd - hGLS + Actin+Ca-ATP
    
  • 1c0g, 1dej - hGLS +Actin (mutant)
    
  • 3a5l, 3a5m, 3a5n, 3a5o - hGLS (mutant)+Actin (mutant)
    
  • 3ci5, 3cip, 1nlv – DdGLS +actin - Dictyostelium discoideum
    
  • 1nm1 - DdGLS +actin+Mg-ATP
    
  • 3cjb - rGLS +rActin
    
  • 3cjc - rGLS +rActin+DNAse I
    
  • 4cbu, 4cbw, 4cbx - mGLS +actin+Ca+ATP
    
• GLS C-terminal
  • 2fh1, 2fh2, 2fh3, 2fh4 – hGLS
    
  • 1p8x - hGLS +Ca
    
  • 1p8z – hGLS fraction+rActin
    

Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Jaime Prilusky, Michal Harel