Structural highlights
3sai is a 2 chain structure with sequence from "bacillus_cereus_var._anthracis"_(cohn_1872)_smith_et_al._1946 "bacillus cereus var. anthracis" (cohn 1872) smith et al. 1946. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
|
| Ligands: | 9DR, NAP, NI, PEG |
| Related: | 3e0b, 3sa2, 3sa1, 3s9u, 3jvx, 3jwm |
| Gene: | BAS2083, BA_2237, dfrA, GBAA2237, GBAA_2237 ("Bacillus cereus var. anthracis" (Cohn 1872) Smith et al. 1946) |
| Activity: | Dihydrofolate reductase, with EC number 1.5.1.3 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
[Q81R22_BACAN] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).[PIRNR:PIRNR000194]
See Also
