5llu | pdb_00005llu
From Proteopedia
Structure of the thermostabilized EAAT1 cryst-II mutant in complex with L-ASP
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Structural highlights
Disease[EAA1_HUMAN] Alternating hemiplegia of childhood;Episodic ataxia type 6. The disease is caused by mutations affecting the gene represented in this entry. Function[EAA1_HUMAN] Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium. Contents | ||||||||||||||||||||
This page was last modified 12:59, 19 April 2017.