Tdp-43

TDP-43 helical stabilizers

spinqualitylabelsall models Compound A is the best current binder to the healthy helical tdp-43 Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D This is the healthy helical coil (residues 307-349) of TDP-43. A key biomolecular cause of ALS appears to be a helix-sheet transition in this area, leading to the formation of protein fibrils. Tdp-43. Function Tdp-43 or TAR DNA-binding protein 43 is a heterogeneous nuclear ribonucleoprotein which has crucial roles in gene expression and alternative splicing, stress response, neuronal functions such as neurite outgrowth and many other cellular processes. Structural highlights This is a sample scene created with SAT to color by Group, and another to make a transparent representation of the protein.

Proteopedia Page Contributors and Editors (what is this?)

Gerry Lushington, Michal Harel