6c0v | pdb_00006c0v

Molecular structure of human P-glycoprotein in the ATP-bound, outward-facing conformation

spinqualitylabelsall models 6c0v, resolution 3.40Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6c0v is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: ATP, MG Activity: Xenobiotic-transporting ATPase, with EC number 3.6.3.44 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease [MDR1_HUMAN] Ulcerative colitis. Disease susceptibility is associated with variations affecting the gene represented in this entry. Function [MDR1_HUMAN] Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.

Proteopedia Page Contributors and Editors (what is this?)

OCA