Negative elongation factor

3D structures of negative elongation factor

Updated on 31-October-2018

5l3x - hNELF A + NELF C/D - human
2bz2, 1x5p, 2jx2 - hNELF E RNA recognition motif - NMR
6gml - NELF A + NELF B + NELF C + NELF D + NELF E + RNA polymerase II + transcription elongation factors SPT4-SPT5 + DNA + RNA + - pig - Cryo EM

References

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

[1] Natarajan M, Schiralli Lester GM, Lee C, Missra A, Wasserman GA, Steffen M, Gilmour DS, Henderson AJ. Negative elongation factor (NELF) coordinates RNA polymerase II pausing, premature termination, and chromatin remodeling to regulate HIV transcription. J Biol Chem. 2013 Sep 6;288(36):25995-6003. doi: 10.1074/jbc.M113.496489. Epub, 2013 Jul 24. PMID:23884411 doi:https://dx.doi.org/10.1074/jbc.M113.496489

[2] Yung TM, Narita T, Komori T, Yamaguchi Y, Handa H. Cellular dynamics of the negative transcription elongation factor NELF. Exp Cell Res. 2009 Jun 10;315(10):1693-705. doi: 10.1016/j.yexcr.2009.02.013., Epub 2009 Feb 23. PMID:19245807 doi:https://dx.doi.org/10.1016/j.yexcr.2009.02.013

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Negative elongation factor

Function

Disease

Structural highlights

3D structures of negative elongation factor

References

Proteopedia Page Contributors and Editors (what is this?)

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