Concanavalin

spinqualitylabelsall models Concanavalin A complex with trisacchride, Mn+2 (small purple), Cl- (large green) and Ca+2 (small green) ions (large purple) (PDB entry 1qdc) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Concanavalin A (ConA) is a carbohydrate-binding protein from jack-bean (Canavalia ensiformis). It binds to certain sugars and to metal. It is used to characterize glycoproteins on cell surfaces. Relevance ConA has therapeutic effect on liver cancer. Structural highlights ConA is the homotetramer with D2 symmetry. ConA contains a metal - Mn+2 and Ca+2 - binding site as well as a sugar binding site.

3D Structures of Concanavalin A

Updated on 18-February-2019

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• Concanavalin A
  • 2uu8, 1nxd, 1gkb, 3enr, 1qny, 1vln, 1jbc, 1cnv, 2cna, 3cna, 3nwk, 5o6n, 6caf – CeConA – Canavalia ensiformis
    
  • 2yz4, 1xqn, 1c57 – CeConA – neutron
    
  • 2ctv – CeConA – Laue
    
  • 1cn1, 1apn, 1dq0, 1dq2 – CeConA demetallized
    
  • 5ygm – CeConA (mutant)
    
  • 2g4i, 2a7a – ConA – Canavalia virosa
    
  • 1wuv – CgConA – Canavalia gladiata
    
  • 3ju9, 1azd – BrConBR – Brazilian jack-bean
    
  • 2cwm - CmConA – Canavalia maritima
    
  • 5byn – ClConA – Canavalia lineata
    
• Concanavalin binary complex
  • 1dq1, 1dq5, 1dq6, 1qgl, 1nls, 1scr, 1scs – CeConA + ion
    
  • 1enq, 1enr, 1ens, 1con, 1dq4, 2enr, 1ces - CeConA demetallized + ion
    
  • 3d4k – CeConA + sugar analog
    
  • 1hqw, 1jyc, 1jyi, 1jui, 1joj, 1jw6 – CeConA + polypeptide
    
  • 1jn2 – CeConA + porphyrin derivative
    
  • 1cjp, 1ona, 1gic, 1val, 1vam, 5cna, 4p9x, 4p9w, 4p9y, 4pf5 – CeConA + pyranoside derivative
    
  • 1i3h, 1qdc, 1qdo, 1bxh, 1tei, 1cvn – CeConA + glucoside
    
  • 5wey – CeConA + mannobiose
    
  • 2p37, 2cy6, 2cyf, 2ow4, 2p34 – CmConA + glucoside
    
  • 2ef6, 2d7f, 2ovu, 2p2k - CgConA + glucoside
    
  • 3qlq - CcConA + glucosyl-octasilsesquioxane – Canavalia cathartica
    
  • 4czs – CcConA + mannose peptide
    
  • 5f5q – CcConA + mannoside
    
  • 4p14 – CbConA + adenine – Canavalia brasiliensis
    
  • 4pcr – CbConA + GABA
    
  • 3snm - ClConA + indole-acetate
    
  • 4i30, 4tys – ClConA + nucleotide
    
  • 4tzd – ClConA + DNA
    
  • 4h55 - BrConA + glucoside
    
  • 4dpn – ClConA + resveratrol
    

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