Agglutinin

spinqualitylabelsall models Agglutinin complex with polysaccharide ofα- and β-mannose, imidazole and Na+ ion (purple) (PDB code 4gk9) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Agglutinins or galactose-inding lectin (AGG) are sugar-binding lectins which cause particles to change from fluid state to thickened-mass state. Agglutinin isolectin or wheat germ agglutinin is a plant protein that binds specifically to sugars expressed by human gastrointestinal epithelial and immune cells. Disease Cold agglutinin disease is a disorder affecting patients with autoimmune anemia. Structural highlights Agglutinin binds polysaccharide composed of α- and β-mannose in its active site. 1st poly-mannose binding site. 2nd poly-mannose binding site. 3rd poly-mannose binding site. 4th poly-mannose binding site. 3D Structures of agglutinin Agglutinin 3D structures

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