Subtilisin

spinqualitylabelsall models Subtilisin (deepskyblue) complex with streptomycin inhibitor (green) and Ca+2 ions (green) (PDB entry 2sic) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Subtilisin is a serine protease. A 77 amino acid propeptide is cleaved from the N-terminus of pro-Sub to create the mature active enzym. See detalis in User:Tommie Hata/Introduction to Protein Engineering-Subtilisin. Selenosubtilisin is a semisynthetic selenoenzyme produced by chemical modification of subtilisin. Savinase is a subtilisin produced from a lentil. Relevance Subtilisin is widely used commercially in detergents. Structural highlights The active site of Sub contains the catalytic triad: Ser-His-Asp. The peptide inhibitor has numerous interactions with Sub and the scissile bond is flanked by Cys-Pro-Met-Val. 3D Structures of Subtilisin Subtilisin 3D structures

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