Toll-like Receptor 3D structures

3D Structures of Toll-like Receptors

Updated on 27-February-2020

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• Toll-like receptor 1
  • 1fyv – hTLR1 TIR domain – human
    
  • 2z7x, 2z81, 2z82 – hTLR1/VLRB.61 + hTLR2/VLRB.61 + lipopeptide
• Toll-like receptor 2
  • 1fyw – hTLR2 TIR domain
    
  • 1fyx, 1o77 - hTLR2 TIR domain (mutant)
    
  • 2z80 – hTLR2/VLRB.61
    
  • 3a79 – hTLR2/VLRB.61 + hTLR6/VLRB.61 + lipopeptide
    
  • 3a7b - mTLR2/VLRB.61 – mouse
    
  • 3a7c - mTLR2/VLRB.61 + PE-DTPA
    
  • 5d3i – mTLR2 + SSL3
    
• Toll-like receptor 3
  • 1ziw, 2a0z – hTLR3 ligand-binding domain
    
  • 5gs0 – hTLR3 ectodomain + antibody
    
  • 2mk9, 2mka – hTLR3 transmembrane domain - NMR
    
  • 3cig – mTLR3 ectodomain
    
  • 3ciy - mTLR3 ectodomain + RNA
    
• Toll-like receptor 4
  • 2z62, 2z63, 2z66, 3ul9 – hTLR4/VLRB.61
    
  • 3ul8, 3ul7 – hTLR4/VLRB.61 (mutant)
    
  • 5nam, 5nao – hTLR4 transmembrane domain - NMR
    
  • 3fxi, 4g8a - hTLR4 extracellular domain + lymphocyte antigen 96
    
  • 3ula - hTLR4/VLRB.61 + lymphocyte antigen 96
    
  • 2z64, 2z65, 5ijc, 5ijd, 3vq1, 3vq2 – mTLR4 extracellular domain+ lymphocyte antigen 96
    
• Toll-like receptor 5B
  • 5gy2 – zfTLR5B N-terminal + flagellin - zebrafish
    
  • 6bxa – zfTLR5B N-terminal + VLR2
    
  • 6bxc – zfTLR5B N-terminal + VLR9
    
  • 3v44 – zfTLR5B/VLRB.61
    
  • 3v47 – zfTLR5B/VLRB.61 + flagellin
    
• Toll-like receptor 6
  • 4om7 – hTLR6 TIR domain
    
• Toll-like receptor 7
  • 5gmf – mTLR7 + guanosine + poly-U - monkey
    
  • 5gmg – mTLR7 + loxoribine + poly-U
    
  • 5gmh – mTLR7 + resiquimod + poly-U
    
• Toll-like receptor 8
  • 3w3g, 5hdh – hTLR8
    
  • 3w3j, 3w3k, 3w3l, 3w3m, 3w3n, 3wn4, 5awa, 5awc, 5awb, 5awd, 4r6a, 4qbz, 4qc0, 5az5 – hTLR8 + agonist
    
  • 4r07, 4r09 – hTLR8 + ORN06
    
  • 4r08 – hTLR8 + RNA
    
  • 4r0a – hTLR8 + uridine
    
  • 5z14, 5z15, 5wyx, 5wyz – hTLR8 + inhibitor
    
• Toll-like receptor 9
  • 3wpb – hoTLR9 - horse
    
  • 3wpc, 3wpd, 3wpe, 5y3j, 5y3k, 5y3l, 5y3m – hoTLR9 + DNA
    
  • 3wpf – mTLR9
    
  • 3wpg, 3wph, 3wpi – mTLR9 + DNA
    
  • 5zln – mTLR9 (mutant) + DNA
    

• Toll-like receptor 10
  • 2j67 – hTLR10 TIR domain
• Toll-like receptor 13
  • 4z0c – mTLR13 + RNA
    

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Michal Harel, Openfox