5fwb | pdb_00005fwb

Human Spectrin SH3 domain D48G, E7F, K60F

spinqualitylabelsall models 5fwb, resolution 1.50Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 5fwb is a 1 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Related: 5fw6, 5fw7, 5fw8, 5fw9, 5fwc Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease [SPTN1_HUMAN] West syndrome. The disease is caused by mutations affecting the gene represented in this entry. Function [SPTN1_HUMAN] Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane. See Also Spectrin

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