Gp120 3D structures

3D structures of Gp120

Updated on 05-August-2020

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• Gp120 from HIV-1; Domains – Clade A/E 1-140; outer – 1-181; RHPA 1-216; V1-V2 118-246; V3 296-331; core 44-492; C5 484-506
  • 3dnl, 3dnn, 3dno, 3tgq, 3tgr, 3tgt, 3tih, 5f4u - Gp120 core
    
  • 5fa2 - Gp120 core (mutant)
    
  • 1meq – GP120 C5 domain – NMR
    
  • 1niz, 1nj0, 2esx, 2esz, 1u6u, 1u6v - GP120 V3 loop – NMR
    
  • 4jpj, 5idl - Gp120 outer domain
    
• Gp120 binary complex
  • 4jb9, 4lsp, 4lsq, 4lsr, 4lsu, 5te6, 5fcu, 5f9w, 5f9o, 5f96, 5cd5, 4xvt - Gp120 Clade A/E + antibody
    
  • 4yc2, 4ybl, 4s1s, 4s1r, 4s1q - Gp120 Clade A/E (mutant) + antibody
    
  • 4i3r, 4i3s, 5kzc, 5if0, 5ies, 4jpv - Gp120 outer domain + antibody
    
  • 5t33 - Gp120 RHPA + antibody
    
  • 3u2s - Gp120 V1V2 region + antibody PG9
    
  • 3se8, 3se9, 3hi1, 3rjq, 4jkp, 4jm2, 4lss, 4lsv, 4ywg, 4xvs, 3ngb, 4ye4, 4rwy, 4jan, 4lst, 5te7, 5f6j, 5te4, 6bf4, 5wb9, 5w6d, 5ukr, 5uem, 5igx, 4dvr - Gp120 + antibody
    
  • 3idx, 3idy, 2ny7. 4jdt, 5fyl, 5fec, 6bck - Gp120 core (mutant) + antibody
    
  • 4rz8, 5f4l, 5f4p, 5f4r - Gp120 core + CD4 mimic
    
  • 4dku, 4dkv - Gp120 core (mutant) + CD4 mimetic
    
  • 4jzw, 4jzz, 4k0a, 4ka2 - Gp120 core + CD4 mimetic miniprotein
    
  • 4jpj, 4rx4 - Gp120 Clade A + antibody
    
  • 3tgs, 4dko, 4dkp, 4dkq, 4dkr - Gp120 core + piperidine derivative
    
  • 5u6e - Gp120 core + pyrrole derivative
    
  • 4dvx, 4dvw, 4dvv, 4dvt, 4dvs - Gp120 core (mutant) + piperazine derivative
    
• Gp120 ternary complex
  • 5kjr - Gp120 Clade A/E + M48U1 peptide + antibody
    
  • 4rfo, 4rfn - Gp120 Clade A/E (mutant) + M48U1 peptide + antibody
    
  • 4h8w - Gp120 Clade A/E + CD4 + antibody
    
  • 3jwd, 3jwo, 2i5y, 2i60 - Gp120 core + hCD4 N terminal + antibody
    
  • 2nxy, 2nxz, 2ny0, 2ny1, 2ny2, 2ny3, 2ny4, 2ny5, 2ny6, 1gc1, 1g9m, 1g9n, 1rzj, 1rzk, 1yyl, 1yym, 2b4c - Gp120 core (mutant) + hCD4 N terminal + antibody
    
  • 5a8h, 5a7x, 4rqs, 4r4h, 4r2g, 4p9h - Gp120 core + hCD4 D1-D2 domain + antibody
    
  • 4laj - Gp120 core + CD4 mimetic miniprotein + antibody
    
  • 5w4l, 6w4m - Gp120 core (mutant) + CD4 mimetic peptide + antibody
    
  • 4r4f, 4r4n - Gp120 core + M48U1 peptide + antibody
    
  • 5v8l, 5v8m, 5uty, 5utf, 5um8, 5jsa, 5js9, 5i8h, 5d9q, 5cjx, 5c7k, 6ccb, 6mft, 6mdt, 6mco, 6d2p, 6ck9, 6ch9, 6ch8, 6ch7 - Gp120 core + Gp41 + antibody
    
  • 5fyk, 5fyj, 4nco, 6nnj, 6nnf, 6nm6 - Gp120 core (mutant) + Gp41 + antibody
    
  • 6cde, 6cdi, 6orn, 6oro, 6orp, 6orq, 6okp, 6nqd, 6nc3, 6nc2, 6mn7, 6e5p, 6cuf, 6cue, 6chb, 5u1f, 5thr, 4cc8, 3j70 - Gp120 core + Gp41 + antibody – Cryo EM
    
  • 3j5m - Gp120 core (mutant) + Gp41 + antibody – Cryo EM
    
• Gp120 from HIV-2 binary complex
  • 5fec, 5cay - Gp120 core (mutant) + CD4
    
• Gp120 from SIV
  • 2bf1, 3fus - Gp120 core
    
  • 3jcc, 3jcb - Gp120 core + CD4 + antibody – Cryo EM
    

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