2g7y | pdb_00002g7y

Human Cathepsin S with inhibitor CRA-16981

spinqualitylabelsall models 2g7y, resolution 2.00Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 2g7y is a 2 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: MO9 Gene: CTSS (HUMAN) Activity: Cathepsin S, with EC number 3.4.22.27 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [CATS_HUMAN] Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Cathepsin 3D structures

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