Retinoid X receptor 3D structures

3D structures of retinoid X receptor

Updated on 14-February-2022

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• Retinoid X receptor α; Domains – DBD 33-115; LBD 223-462
  • 3nsp, 6hn6, 1g1u - hRXR LBD – human
    
  • 1rxr – hRXR DBD (mutant) – NMR
    
  • 2q60 – RXR LBD – Polyandrocarpa misakiensis
    
• Retinoid X receptor α binary complex
  • 4cn2, 4cn3, 4cn5, 4cn7, 1by4, 6fbr, 6fbq - hRXR DBD + DNA
    
  • 1g5y, 4zhs - hRXR LBD + retinoid
    
  • 1fby - hRXR LBD + 9-cis retinoic acid
    
  • 3nsq - hRXR LBD + antagonist
    
  • 5zqu, 7cfo - hRXR LBD + naphthalene derivative
    
  • 6jno - hRXR LBD + ligand
    
  • 3fug, 5mk4 - hRXR LBD + NCOA2 peptide
    
  • 6jnr - hRXR LBD + SRC1 peptide
    
  • 3fc6 – hRXR LBD + NR1H3 protein
    
  • 3r29 - hRXR LBD + corepressor peptide SMRT2
    
  • 4n5g, 4n8r, 5tbp - hRXR LBD + modulator
    
  • 4ozr, 4ozt - hRXR LBD + ecdysone receptor
    
  • 4j5w - hRXR LBD + orphan nuclear receptor PXR
    
  • 6xwh - hRXR DBD + DR0 response element
    
  • 1dkf – mRXR LBD + mRAR LBD – mouse
    
• Retinoid X receptor α ternary complex
  • 1dsz - hRXR LBD + hRAR LBD + DNA
    
  • 3a9e, 7aos - hRXR LBD + hRAR LBD + NCOA2 peptide
    
  • 3r2a - hRXR LBD + corepressor peptide SMRT2 + antagonist
    
  • 3h0a, 1fm6, 1fm9, 1k74, 5ji0 - hRXR LBD + PPAR-γ + 9-cis retinoic acid + NCOA2 peptide
    
  • 1rdt - hRXR LBD + PPAR-γ + NCOA2 peptide
    
  • 3oap, 4zhs - hRXR LBD + 9-cis retinoic acid + NCOA2 peptide
    
  • 5mmw, 5mku, 5mkj, 5mj5 - hRXR LBD + honokiol derivative + peptide
    
  • 3ozj - hRXR LBD + bigelovin + NCOA2 peptide
    
  • 3pcu - hRXR LBD + rutamarin + NCOA2 peptide
    
  • 7a77 - hRXR LBD + palmitate + NCOA2 peptide
    
  • 2zxz, 2zy0, 3r5m, 1mzn, 1mv9, 1mvc, 4k4j, 4k6i, 4m8e, 4m8h, 5lyq, 7b88, 7b9o - hRXR LBD + agonist + NCOA2 peptide
    
  • 2acl - hRXR LBD + agonist + oxysterols receptor α
    
  • 6sjm - hRXR LBD + biphenyl + NCOA2 peptide
    
  • 3kwy - hRXR LBD + triphenyltin + NCOA2 peptide
    
  • 3e94 - hRXR LBD + tributylin + NCOA2 peptide
    
  • 2p1t, 2p1u, 2p1v, 4rfw, 4rmc, 4rme, 4rmd - hRXR LBD + retinoid + NCOA2 peptide
    
  • 5ec9 - hRXR LBD + coactivator TIF2 peptide + activator
    
  • 4oc7 - hRXR LBD + acrylic acid derivative + NCOA2 peptide
    
  • 5ec9 - hRXR LBD + benzofuran derivative + NCOA2 peptide
    
  • 6sti - hRXR LBD + naphthalene derivative + NCOA2 peptide
    
  • 4poh, 4poj, 4pp3, 4pp5 - hRXR LBD + trienoic acid derivative + NCOA2 peptide
    
  • 1xls - hRXR LBD (mutant) + orphan nuclear receptor NR1I3 + NCOA2 peptide
    
  • 4j5x - hRXR LBD + orphan nuclear receptor PXR + phosphonic acid derivative
    
  • 1r0n, 1ynw - hRXR DBD + DR3 response element + vitamin D3 receptor
    
  • 6xwg - hRXR DBD + DR3 response element + RAR-a
    
• Retinoid X receptor α quaternary complex
  • 3dzu, 3dzy, 3e00 - hRXR LBD + PPAR-γ + 9-cis retinoic acid + NCOA2 peptide + DNA
    
  • 5uan - hRXR LBD + RAR + 9-cis retinoic acid + NCOA2 peptide + DNA
    
  • 5z12 - hRXR LBD + 9-cis retinoic acid + NCOA2 peptide + bile acid receptor
    
  • 6a60, 6a5z - hRXR LBD + 9-cis retinoic acid + oxazol derivative + NCOA1 peptide + bile acid receptor
    
  • 6a5y - hRXR LBD + 9-cis retinoic acid + thiazol derivative + NCOA1 peptide + bile acid receptor
    
  • 4zo1 - hRXR + NCOA2 peptide + thyroid hormone receptor β
    
  • 3uvv - hRXR LBD + 9-cis retinoic acid + thyronine + thyroid hormone receptor α
    
  • 4zo1 - hRXR LBD + NCOA2 peptide + thyroid hormone + thyroid hormone receptor β
    
  • 3fal - hRXR LBD + modulator + oxysterols receptor α + 9-cis retinoic acid
    
  • 1xv9 - hRXR LBD + orphan nuclear receptor NR1I3 + pregnane + NCOA2 peptide
    
  • 1xvp - hRXR LBD + orphan nuclear receptor NR1I3 + CITCO + NCOA2 peptide
    
  • 4nqa - hRXR DBD + DR4 response element + liver X nuclear receptor + NCOA2 peptide
    
• Retinoid X receptor β
  • 1uhl - hRXR LBD + oxysterols receptor α + NCOA2 peptide
    
  • 1h9u – hRXR LBD + agonist
    
  • 5hjp, 5i4v - hRXR LBD + oxysterols receptor LXR-β + agonist
    
  • 7a78 - hRXR LBD + palmitate + NCOA2 peptide
    
  • 5kyj, 5kya - hRXR LBD (mutant) + oxysterols receptor LXR-β + modulator
    
  • 1xdk - mRXR LBD + mRAR LBD + thyroid receptor associated protein
    
• Retinoid X receptor γ
  • 2gl8 – hRXR LBD
    
  • 7a79 - hRXR LBD + palmitate + NCOA2 peptide
    

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Michal Harel