1v5s | pdb_00001v5s

Solution structure of kinase associated domain 1 of mouse MAP/microtubule affinity-regulating kinase 3

spinqualitylabelsall models 1v5s, 20 NMR models Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 1v5s is a 1 chain structure with sequence from Lk3 transgenic mice. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Related: 1ul7 Gene: RIKEN cDNA 1600015G02 (LK3 transgenic mice) Activity: Erythritol kinase, with EC number 2.7.1.27 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN Function [MARK3_MOUSE] Involved in the specific phosphorylation of microtubule-associated proteins for tau, MAP2 and MAP4. Phosphorylates CDC25C. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus (By similarity). Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Serine/threonine protein kinase 3D structures

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