Thrombin 3D Structures
From Proteopedia
Revision as of 10:25, 21 April 2022 by Michal Harel (talk | contribs)
3D Structures of thrombin
Updated on 21-April-2022 - For a general description of the protein see Thrombin
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- Thrombin
- 3r3g, 3gic - hThr HC + LC - human
- 3jz1, 3jz2, 2od3, 6pxq, 6pxj - hThr HC + LC (mutant)
- 7sr9 - hThr HC (mutant) + LC (mutant)
- 3qgn, 4rkj, 5jdu, 6pxq, 6pxj, 3ee0, 2a0q, 1sg8, 1sgi, 1jou - hThr HC (mutant) + LC
- 2hnt– hThr-γ HC + LC
- 3pmb - bThr HC + LC – bovine
- 2ocv - mThr HC + LC - mouse
- 3edx, 3hk3, 3hk6 - mThr HC (mutant) + LC
- 3r3g, 3gic - hThr HC + LC - human
- Thrombin complexes with small molecule
- 1bhx, 1abj, 1ppb - hThr HC + LC + inhibitor
- 4rn6 - hThr HC (mutant) + inhibitor
- 3dd2 - hThr HC + LC + RNA
- 1hao, 1hap, 1hut - hThr HC + LC + DNA
- 3bf6 - hThr HC + LC + suramin
- 1xmn - hThr HC + LC + heparin
- 2h9t - hThr HC + LC + suramin + PPACK
- 1z8i, 1z8j - hThr HC + LC (mutant) + PPACK
- 1sfq, 1shh, 2thf, 1thp, 1b7x, 4rko - hThr HC (mutant) + LC + PPACK
- 1ook, 6v64 - hThr HC + LC + PPACK
- 2hpp, 2hpq - hThr HC + LC + PThr residues 214-292 + PPACK
- 3pma – bThr HC + LC residues 336-364 + sucrose octasulfate
- 1uvs, 1uvt, 1uvu - bThr HC + LC + inhibitor
- 1etr, 1ets, 1ett – bThr-ε HC + LC + inhibitor
- 1bhx, 1abj, 1ppb - hThr HC + LC + inhibitor
- Thrombin complexes with peptide
- 5gim - hPThr HC + LC + peptide
- 3hkj - hThr HC (mutant) + LC + proteinase-activated receptor 1 peptide
- 1de7 - hThr HC + LC + factor XIII activation peptide
- 1fph - hThr HC + LC + fibrinogen peptide
- 3bv9 - hThr HC (mutant) + LC + peptide inhibitor
- 2a2x, 1eb1, 1h8i, 1h8d, 1dit, 1hbt, 3u8t - hThr HC + LC + peptide inhibitor
- 1g37, 1eoj, 1eol, 1nrn, 1nro, 1nrp, 1nrq, 1nrr, 1nrs - hThr HC + peptide inhibitor
- 1hlt - hThr HC + LC + thrombomodulin peptide
- 4ch2, 4ch8 - hThr HC + LC + platelet glycoprotein IB α chain peptide
- 2ank, 3po1 - hThr HC + LC + peptide + inhibitor
- 1dlk - bThr HC + LC + peptide inhibitor
- 1ycp, 1bbr – bThr-ε HC + LC + fibrinogen peptide
- 1ucy - bThr HC + LC + fibrinogen peptide
- 3hki - mThr HC (mutant) + LC + proteinase-activated receptor 1 peptide
- 2pux - mThr HC + LC + proteinase-activated receptor 3 peptide
- 2pv9 - mThr HC (mutant) + LC + proteinase-activated receptor 4 peptide
- 1dm4 - mThr HC (mutant) + LC + fibrinogen peptide
- 5gim - hPThr HC + LC + peptide
- Thrombin complexes containing hirudin
- 3c27, 2zc9, 2zda, 2zdv, 3egk, 2r2m, 2v3h, 2v3o, 2pks, 3eq0, 3dt0, 3dux, 3da9, 3dhk, 2znk, 2zo3, 3d49, 2zhe, 2zhf, 2zhw, 2zg0, 2zfq, 2zfr, 2zhq, 2zi2, 2ziq, 2zff, 2zfp, 2zgb, 2zgx, 2zf0, 3biu, 3biv, 2uuj, 2uuk, 2jh0, 2jh5, 2jh6, 2gde, 2bxt, 2bxu, 2bvr, 2bvs, 2bvx, 2bdy, 2feq, 2c8w, 2c8x, 2c8y, 2c8z, 2c90, 2c93, 2cf8, 2cf9, 2anm, 2w7g, 2fes, 1ype, 1ypg, 1ypj, 1ypk, 1ypl, 1ypm, 1vzq, 1way, 1wbg, 1riw, 1mu6, 1mu8, 1mue, 1nzq, 1o0d, 1oyt, 1o2g, 1gj4, 1gj5, 1kts, 1ktt, 1ghv, 1ghw, 1ghx, 1ghy, 1c5n, 1c5o, 1c4y, 1d3d, 1d3p, 1d3q, 1d3t, 1c4u, 1c4v, 1c1u, 1c1v, 1c1w, 1qj1, 1qj6, 1qj7, 1qhr, 1qur, 1d4p, 1ba8, 1bb0, 1ca8, 1awf, 1awh, 1bcu, 1a61, 1a3b, 1a3e, 1a46, 1a5g, 1b5g, 1tbz, 1a4w, 1ay6, 1ae8, 1afe, 1ad8, 1ai8, 1aix, 1bmm, 1bmn, 1lhc, 1lhd, 1lhe, 1lhf, 1lhg, 1uma, 1aht, 1fpc, 1w7g, 3ldx, 3p17, 3qto, 3qtv, 3qwc, 3qx5, 3rlw, 3rly, 3rm0, 3rm2, 3rml, 3rmm, 3rmn, 3rmo, 3t5f, 3sv2, 3si3, 3si4, 3sha, 3shc, 3u98, 3u9a, 3uwj, 4e7r, 6eo8, 6eo9, 4loy - hThr HC + LC + hirudin peptide + inhibitor
- 7kme – hThr-a HC + LC + hirudin peptide + protein inhibitor
- 7ac9 – hThr HC + LC + hirudin peptide + Arg
- 1zgi, 1zgv, 1zrb, 1z71, 1xm1, 1sl3, 1ta2, 1ta6, 1nm6, 1nt1, 1doj, 1d9i, 1d6w, 1qbv, 1tmu, 1dwb, 1dwc, 1dwd, 1dwe, 4baq, 4bao, 4ban, 4bak, 4bam, 4bah, 5lpd, 5ahg, 5afz, 5afy, 5af9, 5a2m, 4yes, 4ufg, 4uff, 4ufe, 4ufd, 4ueh, 4ue7, 4udw, 4ud9 - hThr HC + hirudin peptide + inhibitor
- 1ny2, 8kme, 7kme, 1a2c, 1tom, 1hdt, 1tmt, 1tmb, 3u8o, 3u8r - hThr HC + LC + hirudin peptide + peptide inhibitor
- 3hat - hThr HC + LC + hirudin peptide + fibrinogen peptide
- 2uuf, 2pw8, 1no9, 1c5l, 1vr1, 4thn, 5gds, 1hxf, 1hxe, 1abi, 1hgt, 1ihs, 1iht, 1thr, 1ths, 2hgt, 3utu, 4ayv, 4ayy, 4az2, 3htc, 4htc - hThr HC + LC + hirudin peptide
- 3vxe, 3vxf - hThr HC + LC + bivalirudin peptide
- 4mlf - hThr HC (mutant) + LC + hirudin peptide
- 5mm6, 5mls, 5mjt - hThr HC (mutant) + LC + hirudin peptide + inhibitor
- 1vit, 1hrt - bThr HC + LC + hirudin peptide
- 3c27, 2zc9, 2zda, 2zdv, 3egk, 2r2m, 2v3h, 2v3o, 2pks, 3eq0, 3dt0, 3dux, 3da9, 3dhk, 2znk, 2zo3, 3d49, 2zhe, 2zhf, 2zhw, 2zg0, 2zfq, 2zfr, 2zhq, 2zi2, 2ziq, 2zff, 2zfp, 2zgb, 2zgx, 2zf0, 3biu, 3biv, 2uuj, 2uuk, 2jh0, 2jh5, 2jh6, 2gde, 2bxt, 2bxu, 2bvr, 2bvs, 2bvx, 2bdy, 2feq, 2c8w, 2c8x, 2c8y, 2c8z, 2c90, 2c93, 2cf8, 2cf9, 2anm, 2w7g, 2fes, 1ype, 1ypg, 1ypj, 1ypk, 1ypl, 1ypm, 1vzq, 1way, 1wbg, 1riw, 1mu6, 1mu8, 1mue, 1nzq, 1o0d, 1oyt, 1o2g, 1gj4, 1gj5, 1kts, 1ktt, 1ghv, 1ghw, 1ghx, 1ghy, 1c5n, 1c5o, 1c4y, 1d3d, 1d3p, 1d3q, 1d3t, 1c4u, 1c4v, 1c1u, 1c1v, 1c1w, 1qj1, 1qj6, 1qj7, 1qhr, 1qur, 1d4p, 1ba8, 1bb0, 1ca8, 1awf, 1awh, 1bcu, 1a61, 1a3b, 1a3e, 1a46, 1a5g, 1b5g, 1tbz, 1a4w, 1ay6, 1ae8, 1afe, 1ad8, 1ai8, 1aix, 1bmm, 1bmn, 1lhc, 1lhd, 1lhe, 1lhf, 1lhg, 1uma, 1aht, 1fpc, 1w7g, 3ldx, 3p17, 3qto, 3qtv, 3qwc, 3qx5, 3rlw, 3rly, 3rm0, 3rm2, 3rml, 3rmm, 3rmn, 3rmo, 3t5f, 3sv2, 3si3, 3si4, 3sha, 3shc, 3u98, 3u9a, 3uwj, 4e7r, 6eo8, 6eo9, 4loy - hThr HC + LC + hirudin peptide + inhibitor
- Thrombin complex with protein
- 2a45 - hThr HC + LC + fibrinogen α, β, γ chains
- 1tb6 - hThr HC + LC (mutant) + antithrombin
- 2b5t - hThr HC (mutant) + LC + antithrombin III (mutant)
- 4dt7 - hThr HC (mutant) + LC + vitamin K-dependent protein C peptide
- 1jmo - hThr HC (mutant) + LC + heparin cofactor II
- 4dy7 - hThr HC (mutant) + LC + glia-derived nexin
- 1e0f - hThr HC + LC + haemadin
- 4boh - hThr HC + LC + madanin
- 4e05, 4e06 - hThr HC + LC + anophelin
- 1dx5 - hThr HC + LC + thrombomodulin
- 3p6z, 3p70 - hThr HC + LC + coagulation factor V
- 7mj5 - hThr HC + LC + XC-43
- 7phx - hThr HC + LC + tsetse coagulation inhibitor
- 3pmh - hThr HC + LC + platelet glycoprotein IB α chain
- 3b23 - hThr HC + LC + variegin
- 6tkj, 6tki, 6tkh - hThr HC + LC + tsetse Thr inhibitor
- 5e8e - hThr HC + LC + antibody
- 2a1d, 1nu7 – bThr HC + LC + staphylocoagulase
- 1avg - bThr HC + LC + triabin
- 1bth - bThr HC (mutant) + LC (mutant) + BPTI
- 1toc - bThr HC + LC + ornithodorin
- 1tbq, 1tbr - bThr HC + LC + rhodniin
- 2a45 - hThr HC + LC + fibrinogen α, β, γ chains
- Prothrombin
- Prothrombin complexes
- 6cym - hPThr HC + LC + inhibitor
- 3qdz – hPThr HC (mutant) + LC + proteinase-activated receptor 4 peptide
- 3lu9, 3bef - hPThr HC + LC (mutant) + proteinase-activated receptor 1 peptide
- 1sr5 - hPThr HC + LC + antithrombin III
- 3k65 - hPThr HC residues 315-622 (mutant) + LC residues 199-314
- 3f68 - hPThr HC residues 364-622 + LC residues 328-363 + hirudin peptide
- 1jwt, 3c1k - hPThr HC + inhibitor
- 4hfp - hPThr HC (mutant) + LC + inhibitor
- 2pgq, 1tq7 - hPThr HC (mutant) + LC + PPACK
- 6gwe, 6t7h - hPThr HC + LC + macrocycle
- 2cn0, 1t4u, 1t4v, 1sb1, 1k21, 1k22, 1g30, 1g32, 1o5g, 3tu7, 4lxb, 5lce, 6tdt, 6eo9, 6eo8, 6zun, 6zuh, 6zug, 6zv7, 6zuu, 6zux, 6zuw, 6zv8, 6i51, 6t3q, 6t4a, 6hsx, 6t3m, 6t52, 6t57, 6t89, 6t8a, 6fjt, 6t54, 6t53 - hPThr HC + LC + hirudin peptide + inhibitor
- 4ax9 - hPThr HC + LC + hirudin peptide
- 1twx - hPThr HC (mutant) + LC + hirudin peptide
- 2hwl - hPThr HC (mutant) + LC + fibrinogen γ’ peptide
- 4i7y, 5ew2, 5ew1, 5cmx, 6eo7, 6eo6, 6gn7, 6evv - hPThr HC + LC + DNA
- 5do4 - hPThr HC + LC + RNA
- 7a0e, 7a0f - bPThr + hirudin peptide
- 6cym - hPThr HC + LC + inhibitor
- Prothrombin complex with protein
- 1id5 - hPThr HC + LC + ecotin
- 1p8v - hPThr HC + LC + platelet glycoprotein IB α chain
- 3gis - hPThr HC residues 364-622 (mutant) + LC residues 315-363 + thrombomodulin
- 3b9f - hPThr HC (mutant) + LC + protein C inhibitor
- 2ody - hPThr HC + LC + boophilin
- 5nhu - hPThr HC + LC + CE5 anticoagulant
- 5l6n - hPThr HC + LC + madanin
- 6tkg, 6tkl - hPThr HC + LC + tsetse Thr inhibitor
- 1id5 - hPThr HC + LC + ecotin
- Prethrombin-1
- 3nxp - hThr residues 199-622
- Prethrombin-2
- Meizothrombin
- 1a0h - bMThr
