Structural highlights
7usx is a 6 chain structure with sequence from Caenorhabditis elegans. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Method: | Electron Microscopy, Resolution 3.09Å |
| Ligands: | 3PE, CA, CLR, D12, MYR, NAG, PEE, R16 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
TMC1_CAEEL Sodium-sensor ion channel that acts specifically in salt taste chemosensation. Required for salt-evoked neuronal activity and behavioral avoidance of high concentrations of NaCl.[1]
References
- ↑ Chatzigeorgiou M, Bang S, Hwang SW, Schafer WR. tmc-1 encodes a sodium-sensitive channel required for salt chemosensation in C. elegans. Nature. 2013 Feb 7;494(7435):95-99. doi: 10.1038/nature11845. Epub 2013 Jan 30. PMID:23364694 doi:https://dx.doi.org/10.1038/nature11845
