Ragulator complex

spinqualitylabelsall models Human ragulator complex proteins: LAMTOR1 coiled coil domain (grey and cyan) + LAMTOR2 roadblock domain (green and red) + LAMTOR3 roadblock domain (pink and gold) + LAMTOR4 roadblock domain (yellow and wheat) + LAMTOR5 roadblock domain (magenta and blue) PDB code 5y39 Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D The ragulator complex (Lamtor) is a pentamer which recruits mTORC1 in the rapamycin (mTOR) signal-transduction pathway and activates it. 3D structures of ragulator complex Ragulator complex 3D structures Updated on 08-October-2023 6b9x - hLAMTOR1 + LAMTOR2 + LAMTOR3 + LAMTOR4 + hepatitis B virus interacting protein - human 5y39, 5y3a, 6ehp, 5x6u - hLAMTOR1 + LAMTOR2 + LAMTOR3 + LAMTOR4 + LAMTOR5 5x6u - hLAMTOR1 (mutant) + LAMTOR2 + LAMTOR3 + LAMTOR4 + LAMTOR5 5yk3 - hLAMTOR1 + LAMTOR2 (mutant) + LAMTOR3 + LAMTOR4 (mutant) + LAMTOR5 6ehr - hLAMTOR1 + LAMTOR2 + LAMTOR3 + LAMTOR4 + LAMTOR5 + Ras-related GTP-binding proteins A, C 5x6v - hLAMTOR1 (mutant) + LAMTOR2 + LAMTOR3 + LAMTOR4 + LAMTOR5 + Ras-related GTP-binding proteins A, C 6wj2, 6wj3 - hLAMTOR1 (mutant) + LAMTOR2 + LAMTOR3 + LAMTOR4 + LAMTOR5 + Ras-related GTP-binding proteins A, C + Na-coupled neutral amino acid transporter 6ulg - hLAMTOR1 + LAMTOR2 + LAMTOR3 + LAMTOR4 + LAMTOR5 + Folliculin + folliculin-interactin protein + Ras-related GTP-binding proteins A, C – Cryo EM 6nzd - hLAMTOR1 (mutant) + LAMTOR2 + LAMTOR3 + LAMTOR4 + LAMTOR5 + Folliculin + folliculin-interactin protein + Ras-related GTP-binding proteins A, C – Cryo EM 6wj2, 6wj3 - hLAMTOR1 (mutant) + LAMTOR2 + LAMTOR3 + LAMTOR4 + LAMTOR5 + sodium-coupled neutral amino acid transporter + Ras-related GTP-binding proteins A,C + GDP – Cryo EM 6u62 - hLAMTOR1 + LAMTOR2 + LAMTOR3 + LAMTOR4 + LAMTOR5 + RAPTOR + Ras-related GTP-binding proteins A, C – Cryo EM 5vok, 5y38, 5yk5 - hLAMTOR4 + LAMTOR5

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