2wwe | pdb_00002wwe

Crystal structure of the phox homology domain of human phosphoinositide-3-kinase-C2-gamma

spinqualitylabelsall models 2wwe, resolution 1.25Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 2wwe is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.25Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function P3C2G_HUMAN Generates phosphatidylinositol 3-phosphate (PtdIns3P) and phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) that act as second messengers (By similarity). May play a role in SDF1A-stimulated chemotaxis (By similarity).[UniProtKB:O70167][UniProtKB:O70173] Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Phosphoinositide 3-kinase 3D structures

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