7ptf | pdb_00007ptf

Pseudomonas aeruginosa DNA gyrase B 24kDa ATPase subdomain complexed with novobiocin

spinqualitylabelsall models 7ptf, resolution 1.32Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7ptf is a 3 chain structure with sequence from Pseudomonas aeruginosa PAO1. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.32Å Ligands: MES, MRD, NOV Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function GYRB_PSEAE A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. See Also Gyrase 3D Structures

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