2qyu | pdb_00002qyu

Crystal structure of Salmonella effector protein SopA

spinqualitylabelsall models 2qyu, resolution 2.10Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 2qyu is a 1 chain structure with sequence from Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.1Å Ligands: B3P, PO4 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function SOPA_SALTY Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is an E3 ubiquitin ligase that interferes with host's ubiquitination pathway. Required for inducing polymorphonuclear leukocytes migration across the intestinal epithelium. Preferentially uses host UBE2D1 (UBCH5A), UBE2D2 (UBCH5B) and UBE2L3 (UBCH7) as E2 ubiquitin-conjugating enzymes. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Ubiquitin protein ligase 3D structures

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