WD-repeat protein 3D structures

3D Structures of WD-repeat protein

Updated on 27-March-2024 - For a general description of the protein see WD repeat-containing protein

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• WDR5
  • 2gnq, 2h68, 2h14, 2h9l, 6ofz, 7axp, 7axq, 7axs, 7axu, 7bed – hWDR5 – human
    
  • 3mxx, 3n0d, 3n0e – hWDR5 (mutant)
    
  • 3smr, 3ur4, 4ia9, 4qqe, 4ql1, 5eal, 5eam, 5eap, 5ear – hWDR5 + piperazine derivative
    
  • 6u5m, 6u5y, 6u6w, 6u80, 6u8b, 6u8l, 6u8o, 6uif, 6uik, 6uj4, 6ujh, 6ujj, 6ujl, 6uoz – hWDR5 + sulfonamide inhibitor
    
  • 5vfc, 6dar, 6das, 6d9x, 6dai, 6dak, 6e1z, 6e1y, 6e22, 6e23, 6ufx, 6ucs, 6pg3, 6pg4, 6pg5, 6pg6, 6pg7, 6pg8, 6pg9, 6pga, 6pgb, 6pgc, 6pgd, 6pge, 6pgf, 6u5m, 6u5y, 6u6w, 6u80, 6u8b, 6u8l, 6u8o, 6ucs, 6ufx, 6uhy, 6uhz, 6uif, 6uik, 6uj4, 6ujh, 6ujj, 6ujl, 6uoz, 7u9y, 7uas – hWDR5 + inhibitor – hWDR5 + inhibitor
    
  • 2cnx, 2co0, 2g99, 2g9a, 2h6k, 2h6n, 2h6q, 2h13, 2h9m, 2h9n, 2h9p, 2o9k, 3psl, 4a7j – hWDR5 + histone H3 peptide
    
  • 4gm3, 4gm8, 4gm9, 4gmb, 6oi0, 6oi1, 6oi2, 6oi3, 6wjq, 7axx, 7cfp, 7dno – hWDR5 + peptide inhibitor
    
  • 2xl2, 2xl3 – hWDR5 + retinoblastoma-binding protein 5 peptide
    
  • 4o45 – hWDR5 + influenza NS1 C-terminal
    
  • 7bcy – hWDR5 + Kaposi sarcoma virus peptide
    
  • 4cy1 – hWDR5 + KAT8 regulatory NSL complex subunit 1+2 peptides
    
  • 4cy2 – hWDR5 + KAT8 regulatory NSL complex subunit 1 peptide
    
  • 4y7r – hWDR5 + Myc MbIIIb peptide
    
  • 3eg6, 3emh, 3uvk, 3uvl, 3uvm, 3uvn, 3uvo, 4erq, 4ery, 4es0, 4esg, 4ewr, 5sxm – hWDR5 + MLL peptide
    
  • 4erz – hWDR5 + MLL4
    
  • 6kiv, 6kiz, 6kiu, 6kix – hWDR5 in MLL1-ubNCP complex - Cryo EM
    
  • 6kiw – hWDR5 in MLL3-ubNCP complex - Cryo EM
    
  • 6pww, 6pwv, 6w5i, 6w5m, 6w5n, 7mbm, 7mbn – hWDR5 in nucleosome complex – Cryo EM
    
  • 7jto, 7jtp, 7q2j – hWDR5 + pVHL + elongin b,c + PROTAC
    
  • 6byn – hWDR5 + monobody
    
  • 3p4f – hWDR5 + retinoblastoma-binding protein 5 peptide + MLL peptide
    
  • 6iam – hWDR5 + small ubiquitin-related modifier 5
    
• WDR9
  • 2q2e – hWDR9 residues 1310-1430
    
• WDR11 or pleckstrin homology domain-interacting protein or PH-interacting protein
  • 3mb3, 7av8, 7av9 – hPHIP second bromodomain residues 1315-1440
    
  • 5enb, 5enc, 5ene, 5enf, 5eni, 5enh, 5enj, 5rji, 5rjj, 5rjk, 5rjl, 5rjm, 5rjn, 5rjo, 5rjp, 5rjq, 5rjr, 5rjs, 5rjt, 5rju, 5rjv, 5rjw, 5rjx, 5rjy, 5rjz, 5rk0, 5rk1, 5rk2, 5rk3, 5rk4, 5rk5, 5rk6, 5rk7, 5rk8, 5rk9, 5rka, 5rkb, 5rkc, 5rkd, 5rke, 5rkf, 5rkg, 5rkh, 5rki, 5rkj, 5rkk, 5rkl, 5rkm, 5rkn, 5rko, 5rkp, 5rkq, 5rkr, 5rks, 5rkt, 5rku, 5rkv, 5rkw, 5rkx, 5rky, 5s8c, 5s8d, 5s8e, 5s8f, 5s8g, 5s8h, 5s8i, 5s8j, 5s8k, 5s8l, 5s8m, 5s8n, 5s8o, 5s8p, 5s8q, 5s8r, 5s8s, 5s8t, 5s8u, 5s8v, 5s8w, 5s8x, 5s8y, 5s8z, 5s90, 5s91, 5s92, 5s93, 5s94, 5s95, 5s97, 5s98, 5s99, 5s9a, 5s9b, 5s9c, 5s9d, 5s9e, 8bw2, 5s9g, 8bw4, 5s9j 8bw3, 5s9j – hPHIP second bromodomain + inhibitor
    
  • 7bbp – hPHIP second bromodomain + histone H4
    
  • 5s96 – hPHIP second bromodomain + salicylic acid
    
• WDR12
  • 6p0q – hWDR12 UBL domain residues 1-87
    
  • 6n31 – hWDR12 residues 90-422
    
• WDR20
  • 5k19 – hWDR20
    
• WDR33 or pre-mRNA 3' end processing protein WDR33
  • 6f9n – hWDR33 residues 35-410 + CPSF160
    
  • 6urg – hWDR33 + CPSF160 + CPSF30 + CPSF100 - Cryo EM
    
  • 6fuw, 6uro – hWDR33 + CPSF160 + CPSF30 + PAS motif - Cryo EM
    
• WDR41
  • 8w3v – hWDR41
    
  • 6lt0, 6v4u – hWDR41 + SMCR8 + C9orf72 - Cryo EM
    
  • 6v4u – hWDR41 + SMCR8 + C9ORF72 – Cryo EM
    
  • 7mge – hWDR41 + SMCR8 + C9ORF72 + ARF1 – Cryo EM
    
• WDR48
  • 5cvl – hWDR48
    
  • 5l8e – hWDR48 + peptide
    
  • 5l8w, 5cvn, 5cvo – hWDR48 + ubiquitin + ubiquitin carboxyl-terminal hydrolase
    
  • 5k1a, 5k1b, 7ay0 – hWDR48 + ubiquitin carboxyl-terminal hydrolase
    
  • 7ay2 – hWDR48 + ubiquitin carboxyl-terminal hydrolase + polyUb
    
  • 5k1c, 6jlq – hWDR48 + WDR20 + ubiquitin carboxyl-terminal hydrolase
    
  • 7ay1 – hWDR48 + FACI + FACD2 + ubiquitin carboxyl-terminal hydrolase + ribosomal protein L40 + DNA – Cryo EM
    
• WDR55
  • 7kqq – hWDR55
    
• WDR60
  • 6rlb, 6sc2 – hWDR60 + WDR34 + dynein + O6-alkylguanine-DNA alkyktransferase - Cryo EM
    
• WDR61
  • 3ow8 – hWDR61
    
  • 7qdr – hWDR61 + SKI2W + tetratricopeptide repeat protein – Cryo EM
    
  • 7qds, 7qdy, 7qdz – hWDR61 + SKI2W + tetratricopeptide repeat protein + RNA – Cryo EM
    
• WDR91
  • 6vyc – hWDR91 residues 392-747
    
• WDR92
  • 3i2n – hWDR92
    
• WDR SLP1
  • 4aez – WDR + mitotic spindle checkpoint component mad2-mad3 - fission yeast
    

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Michal Harel, Jaime Prilusky, Joel L. Sussman