8jbe | pdb_00008jbe

CryoEM Structure of metazoan Mon1-Ccz1-RMC1 complex

spinqualitylabelsall models 8jbe, resolution 3.25Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8jbe is a 3 chain structure with sequence from Drosophila. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.25Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function RMC1_DROME Positive regulator of the Rab7 guanyl-nucleotide exchange activity of the Mon1-Ccz1 complex, possibly by enhancing its endosomal membrane association (PubMed:32391792, PubMed:32499409). As part of the Mon1-Ccz1 complex involved in endolysosomal biogenesis possibly by mediating Rab conversion, the replacement of Rab5 with Rab7 during late endosome maturation (PubMed:32499409).

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