Updated on 14-August-2024
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- Squalene synthase
- 3vj8, 3vjb – hSQS – human
- 1ezf – hSQS (mutant)
- 4hd1 – SQS – Alicyclobacillus acidocaldarius
- Squalene synthase complexes
- 3lee – hSQS + Mg + bisphosphonate inhibitor
- 3asx, 3q2z, 3q30 – hSQS + Mg + PO4 + inhibitor
- 3vj9, 3vja – hSQS + Ni
- 3vjc – hSQS + Mg + PO4 + zaragozic acid
- 3v66 – hSQS + PO4 + inhibitor
- 3wef – hSQS + FPP analog
- 3weg – hSQS + Mg + FPP analog
- 3weh – hSQS + Mg + presqualene pyrophosphate
- 3wei – hSQS (mutant) + Mn + presqualene pyrophosphate
- 3wej, 3wek – hSQS (mutant) + Mg + presqualene pyrophosphate
- 3wc9 – hSQS (mutant) + farnesyl thiopyrophosphate
- 3wcd – hSQS (mutant) + phenoxy thiocyanate derivative
- 3wcf, 3wch, 3wci, 3wcl – hSQS (mutant) + imidazole phosphonate derivative
- 3wcj – hSQS (mutant) + pyrrolidine derivative
- 3wcm – hSQS (mutant) + pyridine derivative
- 3wsa, 3wsb – hSQS (mutant) + tuberculosis drug
- 3wef, 3weg – hSQS + FPP analog
- 3weh – hSQS + presqualene pyrophosphate
- 3wei, 3wej, 3wek – hSQS (mutant) + presqualene pyrophosphate
- 3wca, 3wcb, 3wcc, 3wce, 3wcg – SQS (mutant) + FPP analog – Trypanosoma cruzi
- 7wgi – AfSQS + PO4 + indole – Aspergillus flavus
- 7wgh – AfSQS (mutant) + POP + PO4 +farnesyl thiopyrophosphate
- Dehydrosqualene synthase (DSQS)
- 3vjd, 2zco – SaDSQS – Staphylococcus aureus
- 3nri – SaDSQS + dehydrosqualene
- 3npr, 3adz – SaSQS + presqualene pyrophosphate
- 3lgz – SaSQS (mutant) + presqualene pyrophosphate
- 3vje – SaDSQS (mutant) + zaragozic acid
- 3ae0 – SaDSQS + geranylgeranyl + thiopyrophosphate
- 3w7f, 5yis – SaDSQS + farnesyl + thiopyrophosphate
- 3acw, 3acx, 3acy, 3tfv, 3tfn, 3tfp, 4f6v, 4f6x, 2zcs, 2zcq, 2zy1, 2zcr, 4e9z, 4e9u, 4ea0, 4ea1, 4ea2 – SaDSQS + inhibitor
