Aldose reductase 3D structures

3D Structures of Aldose Reductase

Updated on 03-July-2025

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• Aldose Reductase or aldo-keto reductase family 1 member B1 or AKR1B1
  • 1abn, 1ads, 3q65 - hAldR +NADP – human
    
  • 2alr – hAldR
    
  • 1xgd – hAldR (mutant)
    
  • 3q67 – hAldR (mutant)+NADP
    
  • 1dla, 1cwn – pAldR - pig
    
  • 1ah4, 3cv7 - pAldR+NADP
    
  • 1hqt – pAldR (mutant) + NADP
    
  • 4gca – AldR – mouse
    
  • 2bgq – bAldR - barley
    
  • 2bgs - bAldR+NADP
    
  • 5jh1, 9ou1 – maAldR – maize
    
  • 5jgw – maAldR + NADP
    
  • 5zci – DnAldR – Debaryomyces nepalensis
    
  • 5zcm – DnAldR + NADP
    
  • 3afm – SsAldR A1-R – Sphingomonas sp.
    
  • 3afn - SsAldR A1-R+NADP
    
  • 3krb – AldR+NADP – Ghiardia lamblia
    
• Aldose Reductase+inhibitors
  • 1el3, 1t40, 1t41, 1us0, 2iki, 2i16, 2i17, 2pev, 2pf8, 2pfh, 2pzn, 2qxw, 2r24, 3g5e, 3ghr, 3ghs, 3ght, 3ghu, 3t42, 4puw, 4puu, 4q7b, 4qbx, 4qr6, 4rpq, 4ys1 - hAldR +NADP+IDD inhibitors
    
  • 6t3p, 6t7q, 6td8, 6txp, 6xum, 6y1p 8auu, 8b34, 8b3n, 8b3r, 8cnf, 8cnp, 8oz2, 8p2r - hAldR (mutant) +NADP+IDD inhibitor + citrate
  • 1az1, 2pdc, 2pdj, 2pdk, 2pdp, 2pdu, 3lbo, 3ld5, 3lep, 3lqg, 3lql, 3lz3, 3lz5, 3m4h, 3m64, 3mc5, 3onb, 3onc, 8b66 - hAldR (mutant)+ NADP + IDD inhibitor
  • 3u2c - hAldR +NADP+ NSAID inhibitor
  • 1ef3, 1iei, 1mar, 1pwl, 1pwm, 1x97, 1x98, 1z3n, 2dux, 2duz, 2dv0, 2fz8, 2fz9, 2fzb, 2fzd, 2hv5, 2hvn, 2hvo, 2pd5, 3bcj, 4jir - hAldR+NADP+inhibitor for diabetic treatment
    
  • 2agt, 2pd9, 2pdb, 2pdf, 2pdi, 2pdl, 2pdm, 2pdw, 2pdx, 2pdy, 3len, 3m0i, 3mb9 – hAldR (mutant) + NADP + inhibitor for diabetic treatment
  • 1z89, 1z8a - hAldR+NADP+sulfonyl-pyridazinone
  • 5ha7 – hAldR (mutant) +NADP+pyrimidine inhibitor
    
  • 4nkc, 4pr4, 4prr, 4prt, 4yu1 – hAldR +NADP+ diphenyl inhibitor
    
  • 5ouj, 5ouk – hAldR + NADP+ quinoine inhibitor
    
  • 2pdg, 2pdh, 4xzi, 4xzh - hAldR+NADP+uracil inhibitor
  • 1x96, 2acs, 2acu, 6f7r, 6f81, 6f82, 6f84, 6f8o - hAldR+NADP+citrate
  • 2acq - hAldR +NADP+glucose phosphate
  • 2acr - hAldR +NADP+cacodylate
  • 2ikg, 2ikh, 2ikj, 3v35 - hAldR+NADP+nitro-substituted inhibitor
  • 3v36 - hAldR+NADP+ glyceraldehyde + azine
  • 2nvc, 2nvd - hAldR+NADP+isothiazole inhibitor
  • 3p2v - hAldR+NADP+ benzothiazepine inhibitor
  • 2ine, 2inz, 2ipw, 2iq0, 2iqd, 2is7, 2isf - hAldR+NADP+ acid
    
  • 2f2k - hAldR+NADP+DEG
  • 2pdn, 2pdq – hAldR (mutant)+NADP+uracil inhibitor
  • 1az2, 6t27, 6t5g, 6y03, 8a4n, 8aqg, 8aqp - hAldR (mutant)+NADP+citrate
  • 3dn5 – hAldR+NADP+biaryl inhibitor
  • 3rx2, 3rx3, 3rx4, 3s3g - hAldR+NADP+ sulindac inhibitor
    
  • 4igs - hAldR+NADP+ polyfluorinated inhibitor
    
  • 8ae9, 8bjl, 8fh5, 8fh6, 8fh7, 8fh9 - hAldR+NADP + inhibitor
    
  • 8fh8 - hAldR+NADP+ H2O2 + inhibitor
    
  • 4lau, 4laz, 4lb3, 4lb4, 4lbr, 4lbs, 4qxi, 6syw, 6tuc, 6tuf - hAldR+NADP+ carbamoyl inhibitor
    
  • 4qx4 - hAldR+NADP+ mercaptotriazinoindole inhibitor
    
  • 3fx4 – pAldR+NADP+thiazolidine derivative
  • 1ae4, 1ah0, 1ah3, 1eko, 3h4g - pAldR+NADP+IDD inhibitor
  • 2vdg – bAldR+NADP+butanol
  • 5jh2 – maAldR + adenosine diphosphate
    

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