Pyruvate carboxylase 3D structures

3D structures of pyruvate carboxylase

Updated on 23-August-2026

{"openlevels":0}

• Pyruvate carboxylase; Domains – biotin carboxylase 1-461; carboxyltransferase (CT) 465-end
  • 7wta, 8hwl, 8j7o – hPC – human – Cryo EM
    
  • 3bg9 - hPC CT domain
    
  • 3tw7 – RePC – Rhizobium etli
    
  • 4jx4 – RePC CT domain
    
  • 1ulz – PC biotin carboxylase domain (mutant) – Aquifex aeolicus
    
  • 2dzd – PC biotin carboxylase domain – Geobacillus thermodenitrificans
    
  • 4qsl – LmPC – Listeria monocytogenes
    
  • 7zz0 - LlPC – Lactococcus lactis – Cryo EM
    
  • 5ks8 – PC subunit a+b – Methylobacillus flagellatus
    
  • 9vmh, 9vvk – MtPC – Mycobactrium tuberculosis – Cryo EM
    
  • 9ueq - MtPC CT domain
    
• Pyruvate carboxylase binary complex
  • 7wtc - hPC + acetyl-CoA – Cryo EM
    
  • 3bg3 - hPC CT domain + pyruvate
    
  • 7zyz - LlPC + oxaloacetate – Cryo EM
    
  • 7zz5 - LlPC + acetyl-CoA – Cryo EM
    
  • 7zz2, 7zz6 - LlPC + pyruvate – Cryo EM
    
  • 5vyw - LlPC + biotin
    
  • 3hb9, 3hbl, 4hnu - SaPC (mutant) + ADP – Staphlococcus aureus
    
  • 4qsh, 4qsk - LmPC + cAMP
    
  • 4mfd - RePC CT domain + oxalate
    
  • 4mim - RePC CT domain + pyruvate derivative
    
• Pyruvate carboxylase ternary complex
  • 8xl9 - hPC + biotin – Cryo EM
    
  • 7wtb, 7wte - hPC + acetyl-CoA + ANP – Cryo EM
    
  • 7wtd, 7zz4 - LlPC + acetyl-CoA + ATP – Cryo EM
    
  • 9ubg - LlPC + acetyl-CoA + ADP – Cryo EM
    
  • 5vyz, 5vz0 - LlPC + ADP + cAMP
    
  • 7zz1 - LlPC + biotin + oxaloacetate – Cryo EM
    
  • 4jx5 – RePC CT domain + pyruvate
    
  • 4jx6 – RePC CT domain (mutant) + pyruvate
    
  • 4m6v – RePC CT domain + pyruvate + biocytin
    
  • 4mfe – RePC CT domain + pyruvate derivative + biotin
    
  • 2qf7 - RePC + acetyl-CoA + AGS
    
  • 3tw6 - RePC (mutant) + acetyl-CoA + ADP
    
  • 4loc - RePC + biotin + oxamate
    
  • 4hnt, 4hnv - SaPC (mutant) + ADP + ATP
    
  • 3ho8, 8gk8 - SaPC + acetyl-CoA + imidazole derivative
    
• Pyruvate carboxylase higher complex
  • 7zyy - LlPC + acetyl-CoA + ATP + pyruvate – Cryo EM
    
  • 7zz8 - LlPC + acetyl-CoA + ADP + cAMP + pyruvate – Cryo EM
    
  • 7zz3 - LlPC + acetyl-CoA + ADP + biotin + pyruvate – Cryo EM
    
  • 3bg5 - SaPC + pyruvate+ imidazole derivative + ATP
    

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel