Quinone reductase 3D structures

Updated on 15-September-2026

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• Quinone reductase type 1
  • 3jsx – hQR1 + coumarine derivative
    
  • 2f1o – hQR1 + dicoumarol
    
  • 1kbo, 1kbq – hQR1 + indole derivative
    
• Quinone reductase type 2 or ribosyldihydronicotinamide dehydrogenase [quinone]
  • 4qod – hNQO2 - human
    
  • 4qof – hNQO2 + FMN
    
  • 1qr2, 3fw1, 4qoe – hNQO2 + FAD
    
  • 3g5m, 3gam, 3o2n – hNQO2 + FAD + PET agent
    
  • 3ovm, 3owh, 3owx – hNQO2 + FAD + carbamate derivative
    
  • 2qwx, 2qx4, 2qx6, 2qx8, 2qx9, 3ox1 – hNQO2 + FAD + acetamide derivative
    
  • 3ox2, 4xdg, 4xdh - hNQO2 + FAD + indole derivative
    
  • 3ox3 - hNQO2 + FAD + carboxamide derivative
    
  • 4u7f, 4u7g, 4u7h - hNQO2 + FAD + imidazole derivative
    
  • 4zvk, 5buc - hNQO2 + FAD + ethidium
    
  • 4zvm - hNQO2 + FAD + doxorubicin
    
  • 2qmy – hNQO2 + FAD + adrenochrome
    
  • 2qr2 – hNQO2 + FAD + menadione
    
  • 2qmz – hNQO2 + FAD + dopamine
    
  • 4qog – hNQO2 + FAD + melatonin
    
  • 1sg0, 4qoh – hNQO2 + FAD + resveratol
    
  • 4qoj – hNQO2 + FMN + resveratol
    
  • 4qoi – hNQO2 + FMN + melatonin
    
  • 3nfr, 3nhf, 3nhj, 3nhk, 3nhl, 3nhp, 3nhr, 3nhs, 3nhu, 3nhw, 3nhy, 3uxe, 3uxh - hNQO2 + FAD + quinoline derivative
    
  • 3te7, 3tem, 3tzb, 4zvl, 4zvn – hNQO2 + FAD + acridine derivative
    
  • 1xi2, 1zx1, 2bzs, 3o73, 5lbw, 5lby, 5lbz – hNQO2 + FAD + anti-cancer prodrug
    
  • 4fgj, 4fgk, 4fgl – hNQO2 + FAD + anti-malaria drug
    
  • 5lbt, 5lbu – hNQO2 + FAD + anti-wart drug
    
  • 4gqi, 4gr9 – hNQO2 + FAD + ligand
    
• Sulfide-quinone reductase or Sulfide-quinone oxidoreductase
  • 6mo6, 6mp5, 6oi5 – hSQR + FAD
    
  • 6oi6, 6oib, 6oic, 6wh6 – hSQR + FAD + CoQ
    
  • 3hyv – AaSQR + FAD – Aquifex aeolicus
    
  • 3hyw – AaSQR + FAD + decylubiquinone
    
  • 3hyx – AaSQR + FAD + Aurachin C
    
  • 3h8i, 3h8l – AaSQR + FAD + trisulfane
    
  • 3t0k – AfSQR + FAD + trisulfide + decylubiquinone - Acidithiobacillus ferrooxidabs
    
  • 3sz0 – AfSQR + FAD
  • 3t14 – AfSQR + FAD + disulfide
    
  • 3t2y – AfSQR (mutant) + FAD + disulfide
    
  • 3szf – AfSQR (mutant) + FAD + trisulfide
  • 3kpk, 3sx6, 3sy4, 3syi - hNQO1 (mutant) + H2S + FAD
  • 3t2k, 3t2z – AfSQR + FAD + trisulfane
    
  • 3t31 – AfSQR + FAD + decylubiquinone
    
  • 3sxi, 3szw – AfSQR (mutant) + FAD + decylubiquinone
  • 3szc – AfSQR + FAD + decylubiquinone + H2S
• NADPH-quinone reductase or NADPH-quinone oxidoreductase or NADP dehydrogenase [quinone]
  • 1d4a, 5ea2, 8rfn, 9ezq, 9ezs - hNQO1 + FAD
    
  • 5a4k, 8c9j - hNQO1 (mutant) + FAD
    
  • 3jsx – hNQO1 + FAD + chromen derivative
    
  • 6fy4 – hNQO1 + FAD + pyrrolidine derivative
    
  • 2f1O, 4cet – hNQO1 + FAD + dicoumarol
    
  • 5fuq – hNQO1 (mutant) + FAD + dicoumarol
    
  • 4cf6 – hNQO1 (mutant) + FAD + cibacron
    
  • 10qv – hNQO1 + FAD + warfarin
    
  • 1yb5 – hNQO1 + NADP
    
  • 8rfm, 9ezr, 9ezt, 9id0 – hNQO1 + NAD
  • 1gg5, 1h66, 1h69, 1qbg, 6llc - hNQRO1 + FAD + anti-cancer prodrug
    
  • 1dxo, 5eai - hNQO1 + FAD + quinone derivative
    
  • 1kbo, 1kbq - hNQO1 + FAD + indole derivative
    
  • 8pqn - hNQO1 + FAD + activator
  • 1dxq - mNQO1 + FAD - mouse
    
  • 3ha2 – NQO1 – Pediococcus pentosaceus
    
• Quinone reductase
  • 1qrd – QR + bicarbon blue + duroquinone - rat
    
• Na(+)-translocating NADH-quinone reductase
  • 8a1t, 8a1x, 8acw, 8acy, 8ad0, 9ud3, 9ud6, 9ud8, 9ud9 – VcNTNQD subunit a-f + FMN + riboflavin + FAD – Vibrio cholera – Cryo EM
    
  • 9u5g, 9ud2, 9ud4 – VcNTNQD subunit a-f (mutant) + FMN + riboflavin + FAD – Cryo EM
  • 8a1v, 8a1w – VcNTNQD subunit a-f + FMN + riboflavin + ubiquinone + FAD – Cryo EM
    
  • 8evu, 8ew3 – VcNTNQD subunit a-f + FMN + riboflavin + ubiquinone – Cryo EM
    
  • 8a1y – VcNTNQD subunit a-f + FMN + riboflavin + quinoline inhibitor + FAD – Cryo EM
    
  • 7xk3, 7xk4, 7xk5 – VcNTNQD subunit a-f + FMN + riboflavin + DOPE + FAD – Cryo EM
    
  • 7xk6, 7xk7 – VcNTNQD subunit a-f + FMN + riboflavin + DOPE + FAD + antibiotic – Cryo EM
    
  • 9lrr, 9uda, 9ud5, 9udf – VcNTNQD subunit a-f (mutant) + FMN + riboflavin + FAD + antibiotic – Cryo EM
  • 9uuu – VcNTNQD subunit a-f + FMN + riboflavin + FAD + NADH – Cryo EM
  • 9udg – VcNTNQD subunit a-f + FMN + riboflavin + FAD + quinolone derivative – Cryo EM
  • 8a1u – VcNTNQD subunit a-f + FMN + riboflavin + ubiquinone + FAD + NADH – Cryo EM
    
  • 4u9o, 4u9q – VcNTNQD subunit a
    
  • 4uaj, 8ad4 – VcNTNQD subunit f + FAD
  • 8acw – VcNTNQD subunit f + NADH + FAD
    
  • 4u9u – VcNTNQD subunit f FAD-binding domain 130-407 + FAD
    
  • 8ad3, 8ad5 – VcNTNQD subunit f FAD-binding domain 130-407 (mutant) + FAD
    
  • 7qu3, 7qu5 – NTNQD subunit f FAD-binding domain 130-407 + FAD – Pseudomonas aeruginosa
    
  • 7qty, 7qu0 – KpNTNQD subunit f FAD-binding domain 130-407 + FAD - Klebsiella pneumoniae
    
  • 4xa7 – NTNQD subunit c 33-261 + FMN – Vibrio Harveyi
  • 3lwx – NTNQD subunit c 73-278 – Parabactrioides distasonis
  • 4xhf – NTNQD subunit c 33-264 – Shewanella oneidensis
• FMN-dependent NADPH-quinone reductase (AZOR) or FMN-dependent NADH-azoreductase
  • 7f76 – AZOR + FMN – Bacillus cohnii

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel