3r8f

Replication initiator DnaA bound to AMPPCP and single-stranded DNA

spinqualitylabelsall models 3r8f, resolution 3.37Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3r8f is a 5 chain structure with sequence from Aquifex aeolicus. The December 2013 RCSB PDB Molecule of the Month feature on DNA Helicase by David Goodsell is 10.2210/rcsb_pdb/mom_2013_12. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 3.366Å Ligands: ACP, MG Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function DNAA_AQUAE Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity). See Also DnaA

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