First time at Proteopedia? Click on the green links, they change the 3D image. Proteopedia is a 3D, interactive encyclopedia of proteins, RNA, DNA and other molecules. With a free user account, you can edit pages in Proteopedia. Visit the Main Page to learn more. Enter the Page of the Year Competition to win a 32GB iPod Touch and other prizes!
1ffk
From Proteopedia
| 1ffk, resolution 2.40Å () | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Ligands: | , , | ||||||||
| Domains: | PRK04243, Ribosomal_L29, rpl7ae, rpl37e, Ribosomal_L22, Ribosomal_L7, RplW, PRK01192, rpl18p, PRK04306, Ribosomal_L6, rpl6p, Ribosomal_L5, rpl5p, Ribosomal_L5_C, rpl39e, rpl37ae, rpl44e, rpl2p, Ribosomal_L2_C, Ribosomal_L2, Ribosomal_L13, PRK04005, rpl15p, RPL18A, Ribosomal_L19e_A, Ribosomal_L24e, rpl10e, rpl3p, PRK12766, rpl14p, rpl24p, rpl4lp | ||||||||
| Related: | 1c04 | ||||||||
| |||||||||
| |||||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT FROM HALOARCULA MARISMORTUI AT 2.4 ANGSTROM RESOLUTION
The large ribosomal subunit catalyzes peptide bond formation and binds initiation, termination, and elongation factors. We have determined the crystal structure of the large ribosomal subunit from Haloarcula marismortui at 2.4 angstrom resolution, and it includes 2833 of the subunit's 3045 nucleotides and 27 of its 31 proteins. The domains of its RNAs all have irregular shapes and fit together in the ribosome like the pieces of a three-dimensional jigsaw puzzle to form a large, monolithic structure. Proteins are abundant everywhere on its surface except in the active site where peptide bond formation occurs and where it contacts the small subunit. Most of the proteins stabilize the structure by interacting with several RNA domains, often using idiosyncratically folded extensions that reach into the subunit's interior.
The complete atomic structure of the large ribosomal subunit at 2.4 A resolution., Ban N, Nissen P, Hansen J, Moore PB, Steitz TA, Science. 2000 Aug 11;289(5481):905-20. PMID:10937989
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
About this Structure
1FFK is a Protein complex structure of sequences from Haloarcula marismortui. Additional information on 1FFK is available in a page on Ribosome at the RCSB PDB Molecule of the Month. Full crystallographic information is available from OCA.
Reference
The complete atomic structure of the large ribosomal subunit at 2.4 A resolution., Ban N, Nissen P, Hansen J, Moore PB, Steitz TA, Science. 2000 Aug 11;289(5481):905-20. PMID:10937989
Page seeded by OCA on Wed Jul 23 11:00:52 2008
