1kxi
From Proteopedia
Jump to: navigation, search
proteopedia linkproteopedia linkSTRUCTURE OF CYTOTOXIN HOMOLOG PRECURSOR
Structural highlights
Function3SOF5_NAJAT Non-cytotoxic protein that does not show lytic and hemolytic activities, but can induce aggregation and fusion of sphingomyelin vesicles (PubMed:8182052). It binds to integrin alpha-V/beta-3 (ITGAV/ITGB3) with high affinity, and it inhibits osteoclast differentiation and bone resorption in mice, probably due to binding to integrin alpha-V/beta-3 (PubMed:16407244).[1] [2] [3] [4] Evolutionary ConservationCheck, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See AlsoReferences
|
Retrieved from "http://proteopedia.org/wiki/index.php/1kxi"
Categories: Large Structures | Naja atra | Chiang C-M | Hsiao C-D | Hsin A-Y | Sun Y-J | Wu W-G