1zvm

From Proteopedia

Crystal structure of human CD38: cyclic-ADP-ribosyl synthetase/NAD+ glycohydrolase

Structural highlights

1zvm is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2.2Å
Ligands:	SO4
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CD38_HUMAN Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.

Evolutionary Conservation

Checkto colour the structure by Evolutionary Conservation, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

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PDB ID 1zvm

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1zvm

From Proteopedia

Crystal structure of human CD38: cyclic-ADP-ribosyl synthetase/NAD+ glycohydrolase

Structural highlights

Function

Evolutionary Conservation

See Also

Contents

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