2al7

Structural highlights

Function

ARL8B_HUMAN May play a role in lysosome motility (PubMed:16537643). May play a role in chromosome segregation (PubMed:15331635).^{[1] [2]}

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

1. ↑ Okai T, Araki Y, Tada M, Tateno T, Kontani K, Katada T. Novel small GTPase subfamily capable of associating with tubulin is required for chromosome segregation. J Cell Sci. 2004 Sep 15;117(Pt 20):4705-15. Epub 2004 Aug 25. PMID:15331635 doi:http://dx.doi.org/10.1242/jcs.01347
2. ↑ Hofmann I, Munro S. An N-terminally acetylated Arf-like GTPase is localised to lysosomes and affects their motility. J Cell Sci. 2006 Apr 15;119(Pt 8):1494-503. Epub 2006 Mar 14. PMID:16537643 doi:http://dx.doi.org/jcs.02958