2az0

Structural highlights

Function

B2_FHV Binds double-strand RNA (dsRNA) with high affinity. Suppresses the host RNA silencing-based antiviral response.^{[1] [2]}

See Also

• Flock house virus protein B2
• P19
• Suppression of RNA Silencing by Viruses
• Tomato aspermy virus protein 2b Suppression of RNA Silencing

References

1. ↑ Li WX, Li H, Lu R, Li F, Dus M, Atkinson P, Brydon EW, Johnson KL, Garcia-Sastre A, Ball LA, Palese P, Ding SW. Interferon antagonist proteins of influenza and vaccinia viruses are suppressors of RNA silencing. Proc Natl Acad Sci U S A. 2004 Feb 3;101(5):1350-5. Epub 2004 Jan 26. PMID:14745017 doi:http://dx.doi.org/10.1073/pnas.0308308100
2. ↑ Chao JA, Lee JH, Chapados BR, Debler EW, Schneemann A, Williamson JR. Dual modes of RNA-silencing suppression by Flock House virus protein B2. Nat Struct Mol Biol. 2005 Nov;12(11):952-7. PMID:16228003 doi:10.1038/nsmb1005