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2hto
From Proteopedia
| 2hto, resolution 1.54Å () | |
|---|---|
| Sites: | |
| Ligands: | |
| Related: | 2htt |
| Resources: | FirstGlance, OCA, PDBsum, RCSB |
| Coordinates: | save as pdb, mmCIF, xml |
Ruthenium hexammine ion interactions with Z-DNA
The hexamer duplex d(CGCGCA).d(TGCGCG) was crystallized with hexammineruthenium(III) ions in an orthorhombic space group; the crystals diffracted to 1.54 A resolution. Strong ion interactions with the adenine base induce a tautomeric shift from the amino to the imino form. Consequently, the A.T base pairing is disrupted. This structural study may be relevant to metal toxicity.
Hexammineruthenium(III) ion interactions with Z-DNA., Bharanidharan D, Thiyagarajan S, Gautham N, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Dec 1;63(Pt, 12):1008-13. Epub 2007 Nov 21. PMID:18084080
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
About this Structure
2HTO is a Protein complex structure. Full crystallographic information is available from OCA.
Reference
Hexammineruthenium(III) ion interactions with Z-DNA., Bharanidharan D, Thiyagarajan S, Gautham N, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Dec 1;63(Pt, 12):1008-13. Epub 2007 Nov 21. PMID:18084080
Page seeded by OCA on Wed Oct 8 09:06:05 2008
