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3gvu
From Proteopedia
| 3gvu, resolution 2.05Å () | |
|---|---|
| Sites: | and |
| Ligands: | |
| Gene: | ABL2 (Homo sapiens) |
| Activity: | Non-specific protein-tyrosine kinase, with EC number 2.7.10.2 |
| Related: | 1fpu
|
| Resources: | FirstGlance, OCA, PDBsum, RCSB |
| Coordinates: | save as pdb, mmCIF, xml |
The crystal structure of human ABL2 in complex with GLEEVEC
Disease
Known disease associated with this structure: Leukemia, acute myeloid, with eosinophilia OMIM:[164690]
About this Structure
3GVU is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Wed Apr 22 11:41:46 2009
Categories: Homo sapiens | Non-specific protein-tyrosine kinase | Arrowsmith, C H. | Barr, A. | Bountra, C. | Chaikuad, A. | Delft, F von. | Edwards, A. | Filippakopoulos, P. | Knapp, S. | Mahajan, P. | Pike, A C.W. | Roos, A. | SGC, Structural Genomics Consortium. | Salah, E. | Savitsky, P. | Shrestha, B. | Ugochukwu, E. | Weigelt, J. | Abelson murine leukemia viral oncogene | Abl | Alternative splicing | Atp-binding | Cell adhesion | Cytoplasm | Cytoskeleton | Kinase | Lipoprotein | Magnesium | Manganese | Metal-binding | Myristate | Nucleotide-binding | Phosphoprotein | Polymorphism | Sgc | Sh2 domain | Sh3 domain | Structural genomic | Structural genomics consortium | Transferase | Tyrosine kinase | Tyrosine-protein kinase
