Structural highlights
Function
IPK_METJA Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. Has no activity with farnesyl phosphate.[1] [2]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
References
- ↑ Grochowski LL, Xu H, White RH. Methanocaldococcus jannaschii uses a modified mevalonate pathway for biosynthesis of isopentenyl diphosphate. J Bacteriol. 2006 May;188(9):3192-8. PMID:16621811 doi:http://dx.doi.org/10.1128/JB.188.9.3192-3198.2006
- ↑ Dellas N, Noel JP. Mutation of Archaeal Isopentenyl Phosphate Kinase Highlights Mechanism and Guides Phosphorylation of Additional Isoprenoid Monophosphates. ACS Chem Biol. 2010 Apr 14. PMID:20392112 doi:10.1021/cb1000313