3q5c

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Crystal structure of four-way junction with sticky end

Structural highlights

3q5c is a 4 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.501Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Publication Abstract from PubMed

We report here the crystal structure of the partially self-complementary decameric sequence d(CGGCGGCCGC), which self assembles to form a four-way junction with sticky ends. Each junction binds to four others through Watson-Crick base pairing at the sticky ends to form a rhombic structure. The rhombuses bind to each other and form two dimensional tiles. The tiles stack to form the crystal. The crystal diffracted in the space group P1 to a resolution of 2.5A. The junction has the anti-parallel stacked-X conformation like other junction structures, though the formation of the rhombic net noticeably alters the details of the junction geometry.

The sequence d(CGGCGGCCGC) self-assembles into a two dimensional rhombic DNA lattice.,Venkadesh S, Mandal PK, Gautham N Biochem Biophys Res Commun. 2011 Apr 15;407(3):548-51. Epub 2011 Mar 16. PMID:21419105[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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References

  1. ↑ Venkadesh S, Mandal PK, Gautham N. The sequence d(CGGCGGCCGC) self-assembles into a two dimensional rhombic DNA lattice. Biochem Biophys Res Commun. 2011 Apr 15;407(3):548-51. Epub 2011 Mar 16. PMID:21419105 doi:10.1016/j.bbrc.2011.03.056

Contents


PDB ID 3q5c

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