Structural highlights
Function
CS2H_ACIS1 Catalyzes the conversion of carbon disulfide into hydrogen sulfide and carbon dioxide, with carbonyl sulfide as an intermediate. Likely plays a key role in sulfur metabolism that allows Acidianus sp. A1-3 to grow on carbon disulfide as the main carbon and energy source. Does not show carbonic anhydrase activity (hydration of CO(2) to carbonate).[1]
References
- ↑ Smeulders MJ, Barends TR, Pol A, Scherer A, Zandvoort MH, Udvarhelyi A, Khadem AF, Menzel A, Hermans J, Shoeman RL, Wessels HJ, van den Heuvel LP, Russ L, Schlichting I, Jetten MS, Op den Camp HJ. Evolution of a new enzyme for carbon disulphide conversion by an acidothermophilic archaeon. Nature. 2011 Oct 19;478(7369):412-6. doi: 10.1038/nature10464. PMID:22012399 doi:10.1038/nature10464