Structural highlights
Function
OTCA_CAMJE Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase (ArgG) involved in the final step in arginine biosynthesis.[1]
See Also
References
- ↑ Shabalin IG, Porebski PJ, Cooper DR, Grabowski M, Onopriyenko O, Grimshaw S, Savchenko A, Chruszcz M, Minor W. Structure of anabolic ornithine carbamoyltransferase from Campylobacter jejuni at 2.7 A resolution. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Sep;68(Pt 9):1018-24. Epub, 2012 Aug 29. PMID:22949186 doi:http://dx.doi.org/10.1107/S1744309112031259